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尿道下裂及其他阴茎异常患者向成年期过渡:会发生什么?

Transitioning patients with hypospadias and other penile abnormalities to adulthood: What to expect?

作者信息

Rourke Keith, Braga Luis H

机构信息

Division of Urology, Department of Surgery, University of Alberta, Edmonton, AB.

Department of Surgery, Division of Urology, McMaster University, Hamilton, ON; Canada.

出版信息

Can Urol Assoc J. 2018 Apr;12(4 Suppl 1):S27-S33. doi: 10.5489/cuaj.5227.

Abstract

Hypospadias patients presenting to adult urologists do so with a wide range of symptoms and problems, including urethral stricture (45-72%), lower urinary tract symptoms (with or without stricture) (50-82%), urethrocutaneous fistula (16-30%), persisting hypospadias (14-43%), micturition spraying (24%), ventral curvature (14-24%), urinary tract infection (15-25%), or lichen sclerosus (13%; range 8-43). Many of these men have concurrent complications as the result of multiple operations and a variety of techniques. Patients with childhood repairs performed by a pediatric urologist are often lost to followup during adolescence and will reemerge in adulthood after what appeared to be a successful pediatric single-stage repair, stressing the need for long-term followup and transitional care. One of the major challenges in successful transitional care is that patients can feel traumatized with feelings of hopelessness surrounding their defects, leaving them hesitant to seek care. As well, these patients often have little knowledge regarding the type of repair or original location of the meatus. Urethral stricture is the most common presenting complication and could be related to various factors, with the clear etiology still under debate. These strictures can fall under four categories based on length, location, and previous surgeries. To lessen the difficulties in transitioning hypospadias patients from pediatric to adult practitioners, followup throughout childhood and adolescence for physical examination, as well as uroflowmetry, is mandatory.

摘要

成年泌尿外科医生接诊的尿道下裂患者会出现各种各样的症状和问题,包括尿道狭窄(45%-72%)、下尿路症状(伴或不伴狭窄)(50%-82%)、尿道皮肤瘘(16%-30%)、持续性尿道下裂(14%-43%)、排尿喷溅(24%)、腹侧弯曲(14%-24%)、尿路感染(15%-25%)或硬化性苔藓(13%;范围为8%-43%)。由于多次手术和多种技术的原因,这些男性中有许多人同时存在并发症。由小儿泌尿外科医生进行儿童期修复的患者在青春期往往失去随访,在看似成功的小儿单阶段修复后,成年期会再次出现问题,这凸显了长期随访和过渡性护理的必要性。成功的过渡性护理面临的主要挑战之一是,患者可能会因对自身缺陷感到绝望而受到创伤,从而不愿寻求治疗。此外,这些患者通常对修复类型或尿道口的原始位置了解甚少。尿道狭窄是最常见的并发症,可能与多种因素有关,其确切病因仍在争论中。根据长度、位置和既往手术情况,这些狭窄可分为四类。为了减轻尿道下裂患者从儿科医生向成年医生过渡的困难,在整个儿童期和青春期进行随访以进行体格检查以及尿流率测定是必不可少的。

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Management of Urethral Strictures After Hypospadias Repair.尿道下裂修复术后尿道狭窄的处理
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Management of adults with prior failed hypospadias surgery.既往尿道下裂手术失败的成人患者的管理。
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