Roh Seung-Young, Choi Jong-Il, Park Sang Hyun, Kim Yun Gi, Shim Jaemin, Kim Jin-Seok, Han Kyung Do, Kim Young-Hoon
Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Medical Center, Seoul, Korea.
Department of Medical Statistics, College of Medicine, Catholic University of Korea, Seoul, Korea.
Korean Circ J. 2021 Oct;51(10):866-874. doi: 10.4070/kcj.2021.0127.
It is crucial to understand the exact public health burden of out-of-hospital cardiac arrest (OHCA) cases; this is presently unknown since sufficient episodes are not reported in registry studies. We aimed to evaluate the epidemiologic features and outcomes of non-traumatic OHCA.
During January 2008 to December 2017, we enrolled 387,665 patients who had been assigned a code for sudden cardiac arrest or had undergone cardiopulmonary resuscitation in the emergency room using the Korean National Health Insurance Service database. Those whose arrest was of non-cardiac origin were excluded.
The incidence of OHCA per 100,000 patients increased steadily from 48.2 in 2008 to, 53.8 in 2011, 60.1 in 2014, and 66.7 in 2017, with a 1-year survival rate of 8.2%. Age and sex-adjusted mortality rates showed a decreasing trend. The hazard ratio was 1.0015 in 2009, 0.9865 in 2012, 0.9769 in 2015, and 0.9629 in 2017 (p for trend <0.0001), with coronary artery disease-related OHCA accounting for 59.8% of the total. Subgroups with coronary artery disease-related OHCA were more likely to be older and have a higher prevalence of all related comorbidities, excluding malignancy, than those with non-coronary artery disease-related OHCA.
This nationwide population-based study showed that the incidence of OHCA in Korea had increased during the last decade. The post OHCA 1-year mortality rate showed a poor outcome but improved gradually.
了解院外心脏骤停(OHCA)病例的确切公共卫生负担至关重要;目前尚不清楚,因为登记研究中未报告足够多的病例。我们旨在评估非创伤性OHCA的流行病学特征和结局。
在2008年1月至2017年12月期间,我们使用韩国国民健康保险服务数据库,纳入了387,665例被赋予心脏骤停代码或在急诊室接受心肺复苏的患者。排除那些非心脏原因导致的骤停患者。
每10万名患者中OHCA的发病率从2008年的48.2稳步上升至2011年的53.8、2014年的60.1和2017年的66.7,1年生存率为8.2%。年龄和性别调整后的死亡率呈下降趋势。2009年的风险比为1.0015,2年为0.9865,2015年为0.9769,2017年为0.9629(趋势p<0.0001),其中冠状动脉疾病相关的OHCA占总数的59.8%。与非冠状动脉疾病相关的OHCA相比,冠状动脉疾病相关的OHCA亚组患者年龄更大,除恶性肿瘤外所有相关合并症的患病率更高。
这项基于全国人群的研究表明,韩国OHCA的发病率在过去十年中有所增加。OHCA后1年死亡率显示预后较差,但逐渐有所改善。