Roh Seung-Young, Choi Jong-Il, Kim Min Sun, Cho Eun Young, Kim Yun Gi, Lee Kwang-No, Baek Yong-Soo, Shim Jaemin, Kim Jin Seok, Park Sang-Weon, Chugh Sumeet S, Kim Young-Hoon
Division of Cardiology, Korea University College of Medicine, Korea University Medicine, Guro hospital, Seoul, Republic of Korea.
Division of Cardiology, Korea University College of Medicine, Korea University Medical Center, Korea University Anam Hospital, Seoul, Republic of Korea.
Pacing Clin Electrophysiol. 2019 Aug;42(8):1086-1094. doi: 10.1111/pace.13741. Epub 2019 Jul 7.
The benefits of implantable cardioverter-defibrillators (ICDs) for the prevention of sudden cardiac arrest (SCA) are well established. However, a significant knowledge gap remains regarding current indications and utilization of ICDs in real-world settings in Asia.
Patients who underwent ICD implantation in South Korea from 2007 to 2015 were identified using the Health Insurance Review and Assessment Service database. We investigated trends in use of ICD for the prevention of SCA.
A total of 4649 ICDs were implanted during 9 years. ICDs were implanted in 1448 (31.2%) patients for primary prevention and in 3201 (68.8%) for secondary prevention. The proportion of ICDs for primary prevention increased from 6.1% in 2007 to 41.9% in 2015. Primary prevention was more frequent in older (≥40 years) recipients (34.4% vs. 14.6%, P < .0001). The rates of ICD implantation for primary prevention were highest for nonischemic dilated cardiomyopathy (55.1%) and lowest (9.7%) for inherited primary arrhythmia syndrome (IPAS).
Our data showed a trend of progressively increasing rates of ICD implantation in Asia, especially for primary prevention of SCA. Primary prevention as an indication for ICD in patients with IPAS remained low.
植入式心脏复律除颤器(ICD)在预防心脏性猝死(SCA)方面的益处已得到充分证实。然而,在亚洲现实环境中,关于ICD目前的适应证和使用情况仍存在重大知识空白。
利用健康保险审查和评估服务数据库确定2007年至2015年在韩国接受ICD植入的患者。我们调查了ICD用于预防SCA的使用趋势。
9年间共植入4649台ICD。1448例(31.2%)患者接受ICD植入用于一级预防,3201例(68.8%)用于二级预防。一级预防的ICD比例从2007年的6.1%增至2015年的41.9%。年龄较大(≥40岁)的接受者中一级预防更为常见(34.4%对14.6%,P <.0001)。非缺血性扩张型心肌病的一级预防ICD植入率最高(55.1%),遗传性原发性心律失常综合征(IPAS)最低(9.7%)。
我们的数据显示亚洲ICD植入率呈逐步上升趋势,尤其是在SCA的一级预防方面。IPAS患者将一级预防作为ICD植入适应证的比例仍然较低。