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创伤性院外心脏骤停患者生存的院前相关因素:一项11年的回顾性队列研究。

Pre-hospital Associated Factors of Survival in Traumatic Out-of-hospital Cardiac Arrests: An 11-Year Retrospective Cohort Study.

作者信息

Laksanamapune Thanakorn, Yuksen Chaiyaporn, Thiamdao Natthaphong

机构信息

Department of Emergency Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.

出版信息

Arch Acad Emerg Med. 2024 Dec 31;13(1):e15. doi: 10.22037/aaem.v13i1.2458. eCollection 2025.

Abstract

INTRODUCTION

Traumatic out-of-hospital cardiac arrest (TOHCA) presents significant public health challenges. The high accident rates and variability in prehospital management in Thailand further complicate TOHCA treatment. This study aimed to analyze prehospital prognostic factors of survival in TOHCA cases.

METHODS

This study is a retrospective cohort study utilizing data from the Information Technology of Emergency Medicine System (ITEMS) from January 2012 to December 2022. It included TOHCA patients who received prehospital care and were transported to the emergency department (ED). We used an exploratory approach, incorporating all prognostic variables into a multivariable logistic regression model. Results are presented as odds ratios (OR) with 95% confidence intervals (CIs) and p-values.

RESULTS

Over an 11-year period, 35,724 patients with the mean age of 39.69±20.53 (range: 1-99) years were included in the final analysis (78.69% male). Of these, 6,590 (18.45%) survived to hospital admission, while 29,134 (81.55%) died in the ED. Prehospital management factors significantly increasing the likelihood of survival to hospital admission included stopping bleeding (OR=1.38, 95% CI=1.24-1.54, P<0.001), endotracheal intubation (ETT) (OR=2.09, 95% CI=1.74-2.50, P<0.001), intravenous fluid administration (OR=1.66, 95% CI=1.35-2.05, P<0.001), defibrillation (OR = 2.35, 95% CI=1.96-2.81, P<0.001), age (aOR = 0.99, 95% CI = 0.98-0.99, P < 0.001), closed fracture (aOR = 0.59, 95% CI = 0.53-0.66, P < 0.001), open fracture (aOR = 0.54, 95% CI = 0.48-0.61, P < 0.001), dislocation (aOR = 0.60, 95% CI = 0.45-0.81, P = 0.001), and on scene time <10 min (aOR = 0.63, 95% CI = 0.54-0.75, P < 0.001).

CONCLUSIONS

To improve survival to hospital admission in TOHCA, several factors should be prioritized. These include administering intravenous fluid boluses, controlling external bleeding, delivering defibrillation when indicated, and performing ETT.

摘要

引言

创伤性院外心脏骤停(TOHCA)带来了重大的公共卫生挑战。泰国的高事故率以及院前管理的差异使TOHCA的治疗更加复杂。本研究旨在分析TOHCA病例中院前生存的预后因素。

方法

本研究是一项回顾性队列研究,利用了2012年1月至2022年12月急诊医学系统信息技术(ITEMS)的数据。研究纳入了接受院前护理并被转运至急诊科(ED)的TOHCA患者。我们采用探索性方法,将所有预后变量纳入多变量逻辑回归模型。结果以比值比(OR)、95%置信区间(CIs)和p值表示。

结果

在11年期间,最终分析纳入了35724例患者,平均年龄为39.69±20.53岁(范围:1 - 99岁),其中男性占78.69%。在这些患者中,6590例(18.45%)存活至入院,而29134例(81.55%)在急诊科死亡。显著增加存活至入院可能性的院前管理因素包括止血(OR = 1.38,95% CI = 1.24 - 1.54,P < 0.001)、气管插管(ETT)(OR = 2.09,95% CI = 1.74 - 2.50,P < 0.001)、静脉输液(OR = 1.66,95% CI = 1.35 - 2.05,P < 0.001)、除颤(OR = 2.35,95% CI = 1.96 - 2.81,P < 0.001)、年龄(校正OR = 0.99,95% CI = 0.98 - 0.99,P < 0.001)、闭合性骨折(校正OR = 0.59,95% CI = 0.53 - 0.66,P < 0.001)、开放性骨折(校正OR = 0.54,95% CI = 0.48 - 0.61,P < 0.001)、脱位(校正OR = 0.60,95% CI = 0.45 - 0.81,P = 0.001)以及现场时间<10分钟(校正OR = 0.63,95% CI = 0.54 - 0.75,P < 0.001)。

结论

为提高TOHCA患者的入院存活率,应优先考虑几个因素。这些因素包括给予静脉推注液体、控制外部出血、在有指征时进行除颤以及实施气管插管。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d13d/11635533/095fbe19ad2c/aaem-13-e15-g001.jpg

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