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新型冠状病毒肺炎与真菌感染:发病机制与治疗相关性。

COVID-19 and fungal infections: Etiopathogenesis and therapeutic implications.

机构信息

Pedro Puerta, Department of Infectious Diseases, Hospital Clinic of Barcelona.

出版信息

Rev Esp Quimioter. 2021 Sep;34 Suppl 1(Suppl1):72-75. doi: 10.37201/req/s01.21.2021. Epub 2021 Sep 30.

DOI:10.37201/req/s01.21.2021
PMID:34598433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8683007/
Abstract

Invasive fungal infection often complicates patients with severe viral infection, especially those admitted to critical care units. Severe SARS-CoV-2 infection has been no exception and a significant association with Aspergillus spp. has been documented, resulting in high patient mortality. In this summary we describe the clinical presentation, the underlying diseases most commonly linked with this association, radiological manifestations and therapeutic management of CAPA.

摘要

侵袭性真菌感染常使重症病毒感染患者复杂化,尤其是入住重症监护病房的患者。严重的严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)感染也不例外,与曲霉菌属(Aspergillus spp.)有显著相关性,导致患者死亡率较高。在本摘要中,我们描述了 CAPA 的临床表现、最常与之相关的基础疾病、影像学表现和治疗管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1716/8683007/79886e7aa705/revespquimioter-34-suppl-1-72-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1716/8683007/79886e7aa705/revespquimioter-34-suppl-1-72-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1716/8683007/79886e7aa705/revespquimioter-34-suppl-1-72-g001.jpg

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Mycoses. 2021 Sep;64(9):1002-1014. doi: 10.1111/myc.13274. Epub 2021 Apr 6.
2
Fatal disseminated aspergillosis in an immunocompetent patient with COVID-19 due to Aspergillus ochraceus.COVID-19 患者因感染土曲霉导致免疫功能正常的致命性播散性曲霉病。
J Mycol Med. 2021 Jun;31(2):101124. doi: 10.1016/j.mycmed.2021.101124. Epub 2021 Feb 23.
3
COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report.
一名日本男性的新型冠状病毒肺炎相关肺曲霉病:病例报告
J Infect Chemother. 2021 Jun;27(6):911-914. doi: 10.1016/j.jiac.2021.02.026. Epub 2021 Feb 25.
4
COVID-19-Associated Pulmonary Aspergillosis, March-August 2020.2020年3月至8月与新型冠状病毒肺炎相关的肺曲霉病
Emerg Infect Dis. 2021;27(4):1077-1086. doi: 10.3201/eid2704.204895. Epub 2021 Feb 4.
5
SARS-CoV-2 and Aspergillus section Fumigati coinfection in an immunocompetent patient treated with corticosteroids.免疫功能正常的患者在接受皮质类固醇治疗时感染 SARS-CoV-2 和烟曲霉属 Fumigati 。
Rev Iberoam Micol. 2021 Jan-Mar;38(1):16-18. doi: 10.1016/j.riam.2020.11.001. Epub 2020 Nov 28.
6
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