Murray D H, Blaisdell F W
Arch Surg. 1978 Apr;113(4):477-80. doi: 10.1001/archsurg.1978.01370160135023.
The advent of synthetic collagen suture (polyglycolic acid and polyglacin 910) has provided a new dimension in surgical suturing. However, surgeons in general have not yet taken full advantage of the potential that this new material offers. Associated evisceration and wound dehiscence rates as well as the incidence rate of wound infection were assessed since these represent standards by which the suture material can be evaluated. In an entire series of 650 cases, there has been one case of wound dehiscence with evisceration. The incidence of infection has been less than 1%, which is comparable to previous experience with interrupted, nonabsorbable sutures. The time required for closure using the new material has been approximately one third of that associated with the use of conventional interrupted closure sutures. This implies a substantial cost reduction for the patient. As a result of this experience, the synthetic absorbable sutures seem to represent the material of choice for routine abdominal or chest wound closure.
合成胶原蛋白缝线(聚乙醇酸和聚甘醇酸910)的出现为外科缝合带来了新的层面。然而,一般来说外科医生尚未充分利用这种新材料所提供的潜力。对相关的肠管脱出和伤口裂开率以及伤口感染发生率进行了评估,因为这些是可以用来评估缝线材料的标准。在总共650例病例中,有1例伤口裂开并伴有肠管脱出。感染发生率低于1%,这与之前使用间断不可吸收缝线的经验相当。使用新材料进行缝合所需的时间约为使用传统间断缝合线的三分之一。这意味着患者的费用大幅降低。基于这一经验,合成可吸收缝线似乎是常规腹部或胸部伤口缝合的首选材料。