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用于神经工程的下一代材料界面。

Next generation material interfaces for neural engineering.

作者信息

Wunderlich Hannah, Kozielski Kristen L

机构信息

Department of Bioengineering and Biosystems, Institute of Functional Interfaces, Karlsruhe Institute of Technology, Karlsruhe, Germany.

Department of Electrical and Computer Engineering, Technical University of Munich, Munich, Germany.

出版信息

Curr Opin Biotechnol. 2021 Dec;72:29-38. doi: 10.1016/j.copbio.2021.09.005. Epub 2021 Oct 1.

DOI:10.1016/j.copbio.2021.09.005
PMID:34601203
Abstract

Neural implant technology is rapidly progressing, and gaining broad interest in research fields such as electrical engineering, materials science, neurobiology, and data science. As the potential applications of neural devices have increased, new technologies to make neural intervention longer-lasting and less invasive have brought attention to neural interface engineering. This review will focus on recent developments in materials for neural implants, highlighting new technologies in the fields of soft electrodes, mechanical and chemical engineering of interface coatings, and remotely powered devices. In this context, novel implantation strategies, manufacturing methods, and combinatorial device functions will also be discussed.

摘要

神经植入技术正在迅速发展,并在电气工程、材料科学、神经生物学和数据科学等研究领域引起了广泛关注。随着神经装置潜在应用的增加,使神经干预更持久、侵入性更小的新技术已将人们的注意力引向神经接口工程。本综述将聚焦于神经植入材料的最新进展,重点介绍软电极、界面涂层的机械和化学工程以及远程供电设备等领域的新技术。在此背景下,还将讨论新颖的植入策略、制造方法和组合式设备功能。

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