Kanti Childrens Hospital, Kathmandu Nepal.
Department of Community Medicine Institute of Medicine IOM, Tribhuvan University, Nepal.
J Nepal Health Res Counc. 2021 Sep 6;19(2):349-354. doi: 10.33314/jnhrc.v19i2.3569.
COVID-19 pandemic hit all age group with different presentations and outcome. This study aimed at exploring the clinical characteristics, investigational findings, hospital outcome along with 90 days follow up of COVID-19 infection in children.
This was longitudinal descriptive study among hospital admitted children with COVID-19 RT-PCR positive during first wave of Pandemic with 90 days telephonic follow up. Demographic and clinical characteristics, comorbidities, SPO2, investigations, need of oxygen , PICU admission, need of ventilator, outcome (improved and discharged, death) and duration of hospital stay were recorded and 90 days telephonic follow up was performed for any illness and hospital admission.
Out of 65 children admitted, male 44 (67.7%) and female 21 (32.3%), median age was 23 months ( IQR 6 days -14 years) with 52( 80.0%) without any comorbid conditions. The common signs were Fever 40(61.5%) vomiting 15 (23.1%) and Cough 11(16.9%).Thirteen (20.0%) children has platelets count less than 150000 and 16(24.6%) had C - reactive protein Positive .Mean duration of hospital stay 8 days (Range 1 -44 days), 20( 30.8% ) needed oxygen , 20(30.8%) needed Pediatric intensive care unit (PICU)admission and 6 (9.2%), needed ventilator. Forty seven (72.3%) recovered and discharged with death of 6.2% (n=4). Fifty six children (75.4%) has not experienced any problem after COVID -19 and only 2 children needed hospital admission in 90 days telephone follow up.
In the first wave of the pandemic, Respiratory and Gastrointestinal symptoms were common presentation with few Severe and critical cases. Majority had good outcome. Majority has no other related illness till 90 days after discharge.
COVID-19 大流行袭击了所有年龄段的人群，表现和结局各不相同。本研究旨在探讨儿童 COVID-19 感染的临床特征、检查结果、住院结局以及 90 天随访情况。
这是一项针对在大流行第一波期间 COVID-19 RT-PCR 阳性住院患儿的纵向描述性研究，进行了 90 天的电话随访。记录人口统计学和临床特征、合并症、血氧饱和度（SPO2）、检查、吸氧需求、PICU 入院、呼吸机需求、结局（改善和出院、死亡）和住院时间，并在 90 天内进行电话随访，以了解任何疾病和住院情况。
65 例住院患儿中，男性 44 例（67.7%），女性 21 例（32.3%），中位年龄为 23 个月（IQR 6 天-14 岁），其中 52 例（80.0%）无任何合并症。常见症状为发热 40 例（61.5%）、呕吐 15 例（23.1%）和咳嗽 11 例（16.9%）。13 例（20.0%）患儿血小板计数低于 150000，16 例（24.6%）C-反应蛋白阳性。住院时间平均为 8 天（范围 1-44 天），20 例（30.8%）需要吸氧，20 例（30.8%）需要儿科重症监护病房（PICU）入院，6 例（9.2%）需要呼吸机。47 例（72.3%）痊愈出院，死亡 6 例（9.2%）。56 例患儿（75.4%）在 COVID-19 后未出现任何问题，仅 2 例患儿在 90 天电话随访时需要住院。
在大流行的第一波中，呼吸道和胃肠道症状是常见表现，少数为严重和危重症病例。大多数患儿结局良好。大多数患儿出院后 90 天内无其他相关疾病。
