利斯特菌单核细胞增生症性踝骨髓炎在阿达木单抗治疗的类风湿关节炎患者中的报告及文献复习：利斯特菌单核细胞增生症性骨髓炎。
Listeria monocytogenes Ankle Osteomyelitis in a Patient with Rheumatoid Arthritis on Adalimumab: A Report and Literature Review of Listeria monocytogenes Osteomyelitis.
机构信息
Department of General Internal Medicine, Teine Keijinkai Hospital, Japan.
Department of Neurology, University Hospitals of Cleveland Medical Center, Case Western Reserve University, U.S.A.
出版信息
Intern Med. 2021;60(19):3171-3176. doi: 10.2169/internalmedicine.5633-20. Epub 2021 Oct 1.
Abstract
Localized Listeria infection predominantly occurs in the prosthetic and hip joints. We herein report a case of Listeria monocytogenes ankle osteomyelitis in a 73-year-old man receiving adalimumab who was transferred to our hospital because of suspected rheumatoid arthritis (RA) flare. He reported a four-month history of left ankle swelling. A surgical biopsy revealed L. monocytogenes osteomyelitis in the left tibia and talus bones. The patient was successfully treated with antibiotics and surgical debridement. Thus, infection due to L. monocytogenes can present as ankle osteomyelitis in immunocompromised patients and may mimic an RA flare.
摘要
局部李斯特菌感染主要发生在假体和髋关节。我们在此报告一例接受阿达木单抗治疗的 73 岁男性的李斯特菌单核细胞增生症性踝关节骨髓炎病例，因疑似类风湿关节炎（RA）发作而转至我院。他报告说，左侧踝关节肿胀已有四个月。手术活检显示左胫骨和距骨有李斯特菌单核细胞增生症性骨髓炎。患者经抗生素和手术清创治疗后痊愈。因此，免疫功能低下患者的李斯特菌感染可表现为踝关节骨髓炎，并可能类似于 RA 发作。
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