显微外科牙髓治疗后根尖周组织再生中的生物材料：一篇叙述性综述。
Biomaterials in periapical regeneration after microsurgical endodontics: A narrative review.
作者信息
Montero-Miralles Paloma, Ibáñez-Barranco Rafael, Cabanillas-Balsera Daniel, Areal-Quecuty Victoria, Sánchez-Domínguez Benito, Martín-González Jenifer, Segura-Egea Juan J, Jiménez-Sánchez María C
机构信息
DDS, MSc, PhD, Professor of Master in Clinical Endodontics, University of Sevilla, C/ Avicena s/n, 41009-Sevilla, Spain.
DDS, MSc, Doctoral fellow, Department of Stomatology, Section of Endodontics, School of Dentistry, University of Sevilla, C/ Avicena s/n, 41009-Sevilla, Spain.
出版信息
J Clin Exp Dent. 2021 Sep 1;13(9):e935-e940. doi: 10.4317/jced.58651. eCollection 2021 Sep.
BACKGROUND
The objective of this narrative review was to analyze the available scientific evidence regarding the application of biomaterials in endodontic microsurgery and its influence in post-surgical tissue repair.
MATERIAL AND METHODS
The review question was Do biomaterials used in endodontic microsurgery influence post-surgical tissue repair and regeneration? Systematic MEDLINE/PubMed review was used to evaluate and present the results.
RESULTS
The search yielded 131 references, 82 of which were selected for full text review after reading the abstracts. After a manual search in the references of the articles selected, 52 references were eliminated. Finally, 30 articles were selected.
CONCLUSIONS
Bone grafts, membranes and bioceramics, especially MTA, are biomaterials with the ability to stimulate periapical tissue regeneration. This is one of many reason why bioceramics are the best choice as retrograde sealing materials. However, microsurgically treated periapical lesions can heal completely without the need to use bone grafts or membranes. Those techniques are indicated in endodontic microsurgery when additional stimulation of tissue regeneration is required, or when bone collapse needs to be prevented. Bioactive endodontic cements, endodontic surgery, periapical repair.
背景
本叙述性综述的目的是分析有关生物材料在牙髓显微外科中的应用及其对术后组织修复影响的现有科学证据。
材料与方法
综述问题为“牙髓显微外科中使用的生物材料是否会影响术后组织修复和再生？”采用系统的MEDLINE/ PubMed检索来评估并呈现结果。
结果
检索得到131篇参考文献，阅读摘要后选择其中82篇进行全文审阅。在对所选文章的参考文献进行人工检索后，排除了52篇参考文献。最终，选定30篇文章。
结论
骨移植材料、膜和生物陶瓷，尤其是MTA，是具有刺激根尖周组织再生能力的生物材料。这是生物陶瓷作为倒充填封闭材料成为最佳选择的众多原因之一。然而，经显微外科治疗的根尖周病变无需使用骨移植材料或膜也可完全愈合。当需要额外刺激组织再生或需要防止骨塌陷时，这些技术适用于牙髓显微外科。生物活性牙髓粘固剂、牙髓外科手术、根尖周修复。
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