Olvera-Rodríguez Valeria, Toussaint-Caire Sonia, Domínguez-Cherit Judith
Escuela de Medicina y Ciencias de la Salud, Instituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey, Mexico.
Servicio de Dermatopatología, Hospital General Dr. Manuel Gea González, Mexico City, Mexico.
Skin Appendage Disord. 2021 Aug;7(5):413-417. doi: 10.1159/000516303. Epub 2021 Jun 1.
The onycholemmal horn is an exceedingly rare subungual tumor characterized by trichilemmal-like keratinization pattern. The only previous instance of onycholemmal horn dates back to 1983 when Haneke reported a keratotic subungual tumor clinically and histologically comparable to a trichilemmal horn. No other case of this condition has been reported so far. We present the case of a 72-year-old female patient, with a history of a slowly growing tumor originating from the nail bed epithelium of the left thumb. The lesion was surgically removed, and pathological examination was consistent with the diagnosis of an onycholemmal horn. Additionally, this study aims to elucidate the correlation between the onycholemmal and trichilemmal keratinization.
甲床角质瘤是一种极其罕见的甲下肿瘤,其特征为具有类似外毛根鞘的角化模式。此前唯一一例甲床角质瘤可追溯到1983年,当时哈内克报告了一例临床和组织学上与外毛根鞘角皮瘤相似的角化性甲下肿瘤。迄今为止,尚未有其他该病症的病例报告。我们报道了一例72岁女性患者,其有一个起源于左手拇指甲床上皮的缓慢生长肿瘤病史。该病变经手术切除,病理检查结果与甲床角质瘤的诊断相符。此外,本研究旨在阐明甲床角质化与外毛根鞘角质化之间的相关性。