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慢性复发性多灶性骨髓炎、视网膜中央动脉阻塞与视神经病变:一种新的关联。

Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association.

作者信息

Vaphiades Michael S, Lai Kevin E, Kline Lanning B, Grondines Brendan, Riser Emily

机构信息

Departments of Ophthalmology, University of Alabama, Birmingham, AL, USA.

Departments of Neurology, University of Alabama, Birmingham, AL, USA.

出版信息

Am J Ophthalmol Case Rep. 2021 Sep 21;24:101209. doi: 10.1016/j.ajoc.2021.101209. eCollection 2021 Dec.

DOI:10.1016/j.ajoc.2021.101209
PMID:34604604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8473659/
Abstract

PURPOSE

To report a patient with chronic recurrent multifocal osteomyelitis (CRMO) complicated by optic neuropathy and central retinal artery occlusion (CRAO).

OBSERVATIONS

CRMO is a noninfectious, inflammatory bone disorder. It is thought to be an autoimmune condition related to an imbalance of pro- and anti-inflammatory cytokines. Retinal vasculitis has been reported in a patient with CRMO but not CRAO or optic neuropathy.

CONCLUSIONS

We expanded the list of ophthalmic involvement of CRMO to include CRAO and optic neuropathy.

摘要

目的

报告一例慢性复发性多灶性骨髓炎(CRMO)并发视神经病变和视网膜中央动脉阻塞(CRAO)的患者。

观察结果

CRMO是一种非感染性炎性骨病。它被认为是一种与促炎和抗炎细胞因子失衡相关的自身免疫性疾病。已有报道CRMO患者出现视网膜血管炎,但未出现CRAO或视神经病变。

结论

我们将CRMO的眼科受累情况扩展至包括CRAO和视神经病变。

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SA J Radiol. 2021 Feb 18;25(1):2030. doi: 10.4102/sajr.v25i1.2030. eCollection 2021.
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What You Need to Know About AQP4, MOG, and NMOSD.AQP4、MOG 和 NMOSD 须知要点。
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Retinal vasculitis with Chronic Recurrent Multifocal Osteomyelitis: a case report and review of the literature.
视网膜血管炎合并慢性复发性多灶性骨髓炎:一例报告并文献复习
BMC Rheumatol. 2019 Aug 1;3:29. doi: 10.1186/s41927-019-0076-5. eCollection 2019.
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Ital J Pediatr. 2018 Feb 17;44(1):26. doi: 10.1186/s13052-018-0463-3.
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Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment.慢性复发性多灶性骨髓炎(CRMO):表现、发病机制与治疗。
Curr Osteoporos Rep. 2017 Dec;15(6):542-554. doi: 10.1007/s11914-017-0405-9.
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