Vaphiades Michael S, Lai Kevin E, Kline Lanning B, Grondines Brendan, Riser Emily
Departments of Ophthalmology, University of Alabama, Birmingham, AL, USA.
Departments of Neurology, University of Alabama, Birmingham, AL, USA.
Am J Ophthalmol Case Rep. 2021 Sep 21;24:101209. doi: 10.1016/j.ajoc.2021.101209. eCollection 2021 Dec.
To report a patient with chronic recurrent multifocal osteomyelitis (CRMO) complicated by optic neuropathy and central retinal artery occlusion (CRAO).
CRMO is a noninfectious, inflammatory bone disorder. It is thought to be an autoimmune condition related to an imbalance of pro- and anti-inflammatory cytokines. Retinal vasculitis has been reported in a patient with CRMO but not CRAO or optic neuropathy.
We expanded the list of ophthalmic involvement of CRMO to include CRAO and optic neuropathy.
报告一例慢性复发性多灶性骨髓炎(CRMO)并发视神经病变和视网膜中央动脉阻塞(CRAO)的患者。
CRMO是一种非感染性炎性骨病。它被认为是一种与促炎和抗炎细胞因子失衡相关的自身免疫性疾病。已有报道CRMO患者出现视网膜血管炎,但未出现CRAO或视神经病变。
我们将CRMO的眼科受累情况扩展至包括CRAO和视神经病变。