Department of Chemistry, Faculty of Sciences, Ilam University, P. O. Box, Ilam 69315-516, Iran.
Anal Methods. 2021 Oct 28;13(41):4904-4910. doi: 10.1039/d1ay01492g.
The present study aimed to report a novel electrochemical sensor through electropolymerization of -aminophenol (-AP) and -dihydroxy benzene (-DB) as monomers on the surface of the glassy carbon electrode (GCE) for the determination of histidine (His) as a template molecule. The developed sensor exhibited satisfactory sensitivity and high selectivity, and also offered a linear range between 0.005 and 10.0 μM with a detection limit of 0.9 nM. Finally, it is worth mentioning that we also aimed at employing the proposed sensor for the detection of His in blood serum samples.
本研究旨在报道一种新型电化学传感器，该传感器通过在玻碳电极（GCE）表面聚合-氨基苯酚（-AP）和-二羟基苯（-DB）作为单体，用于测定组氨酸（His）作为模板分子。所开发的传感器表现出令人满意的灵敏度和高选择性，并且在 0.005 至 10.0 μM 之间具有线性范围，检测限为 0.9 nM。最后，值得一提的是，我们还旨在利用所提出的传感器检测血清样品中的 His。
