Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, P.R. China.
Analyst. 2013 Oct 21;138(20):5949-55. doi: 10.1039/c3an01190a. Epub 2013 Aug 13.
In this study, we developed a novel molecularly-imprinted electrochemical sensor based on a glassy carbon electrode (GCE) decorated by graphene-Prussian blue (GR-PB) composites for the selective and sensitive determination of butylated hydroxyanisole (BHA). The molecularly-imprinted polymers (MIPs) were synthesized by BHA and pyrrole as the template molecule and functional monomer, respectively. Also, the MIPs were assembled on the surface of the GR-PB/GCE by electropolymerization. The sensor was characterized by cyclic voltammetry (CV), scanning electron microscopy (SEM), electrochemical impedance spectroscopy (EIS) and chronoamperometry. It was confirmed that the synergistic effects of GR and PB could improve the electrochemical response and the sensitivity of the sensor. The linear range of the sensor was from 9 × 10(-8) mol L(-1) to 7 × 10(-5) mol L(-1), with a limit of detection (LOD) of 7.63 × 10(-8) mol L(-1) (S/N = 3). The proposed sensor displayed high selectivity, excellent stability and good reproducibility for the determination of BHA. It was successfully applied to the determination of BHA in real samples.
在这项研究中，我们开发了一种基于玻碳电极（GCE）的新型分子印迹电化学传感器，该传感器由石墨烯-普鲁士蓝（GR-PB）复合材料修饰，用于选择性和灵敏地测定丁基羟基茴香醚（BHA）。印迹聚合物（MIPs）是由 BHA 和吡咯分别作为模板分子和功能单体合成的。此外，MIPs 通过电化学聚合组装在 GR-PB/GCE 表面上。通过循环伏安法（CV）、扫描电子显微镜（SEM）、电化学阻抗谱（EIS）和计时电流法对传感器进行了表征。证实了 GR 和 PB 的协同作用可以提高传感器的电化学响应和灵敏度。传感器的线性范围为 9×10(-8) mol·L(-1)至 7×10(-5) mol·L(-1)，检测限（LOD）为 7.63×10(-8) mol·L(-1)（S/N = 3）。该传感器对 BHA 的测定具有高选择性、优异的稳定性和良好的重现性。它已成功应用于实际样品中 BHA 的测定。
