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儿童 COVID-19 的胃肠道、肝脏和胰腺表现。

Gastrointestinal, hepatic and pancreatic manifestations of COVID-19 in children.

机构信息

Department of Health Science, Meyer Children's Hospital, Firenze, Italy.

NEUROFARBA Department, Meyer Children's Hospital, Firenze, Italy.

出版信息

Clin Res Hepatol Gastroenterol. 2022 Apr;46(4):101818. doi: 10.1016/j.clinre.2021.101818. Epub 2021 Oct 2.

DOI:10.1016/j.clinre.2021.101818
PMID:34607068
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8486685/
Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a well-established respiratory tract pathogen. Recent studies in adults and children have shown an increasing number of patients reporting gastrointestinal manifestations of SARS-CoV-2 infection such as diarrhoea, nausea, vomiting and abdominal pain. SARS-CoV-2 RNA can be detected in faeces for an extended period, even after respiratory samples have tested negative and patients are asymptomatic. However, faecal-oral transmission has not yet been proven. In this article, the latest evidence on gastrointestinal, hepato-biliary, and pancreatic manifestations in children with coronavirus disease-19 and multisystem inflammatory syndrome will be analysed.

摘要

严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）是一种成熟的呼吸道病原体。最近的研究表明，越来越多的成年人和儿童报告了 SARS-CoV-2 感染的胃肠道症状，如腹泻、恶心、呕吐和腹痛。SARS-CoV-2 RNA 可在粪便中长时间检测到，甚至在呼吸道样本检测为阴性且患者无症状后也是如此。然而，粪-口传播尚未得到证实。本文将分析目前关于儿童 2019 冠状病毒病和多系统炎症综合征中胃肠道、肝胆和胰腺表现的最新证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf67/8486685/586e91e0cdf4/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf67/8486685/673d2a97bbbd/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf67/8486685/586e91e0cdf4/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf67/8486685/673d2a97bbbd/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf67/8486685/586e91e0cdf4/gr2_lrg.jpg

相似文献

[1]
Gastrointestinal, hepatic and pancreatic manifestations of COVID-19 in children.

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[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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引用本文的文献

[1]
Altered Gut Microbiota and Predicted Immune Dysregulation in Early Childhood SARS-CoV-2 Infection.

Microorganisms. 2025-8-12

[2]
Susceptibility of SARS-CoV2 infection in children.

Eur J Pediatr. 2023-11

[3]
Clinical Characteristics and Laboratory Findings in Children with Multisystem Inflammatory Syndrome (MIS-C)-A Retrospective Study of a Tertiary Care Center from Constanta, Romania.

Healthcare (Basel). 2023-2-12

[4]
Diagnostic and Therapeutic Radiology of the GI Tract, Liver, and Pancreas in Patients with COVID.

Gastroenterol Clin North Am. 2023-3

[5]
The Effect of Acotiamide on Nausea as a Symptom of Chronic Nausea and Vomiting Syndrome after Coronavirus Disease 2019.

Intern Med. 2023-3-1

[6]
Liver and Pancreatic Involvement in Children with Multisystem Inflammatory Syndrome Related to SARS-CoV-2: A Monocentric Study.

Children (Basel). 2022-4-18

[7]
Diagnosis of Multisystem Inflammatory Syndrome in Children in a Resource-Limited Center.

Cureus. 2022-2-15

本文引用的文献

[1]
COVID-19 in celiac disease: a multicentric retrospective cohort study.

Eur Rev Med Pharmacol Sci. 2021-6

[2]
New Onset of Hepatic Steatosis Post-Severe Multisystem Inflammatory Syndrome in Children (MIS-C): A Case Report.

Int J Environ Res Public Health. 2021-6-29

[3]
Challenges in Maternal and Child Health Services Delivery and Access during Pandemics or Public Health Disasters in Low-and Middle-Income Countries: A Systematic Review.

Healthcare (Basel). 2021-6-30

[4]
Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines.

N Engl J Med. 2021-7-22

[5]
An International Reporting Registry of Patients With Celiac Disease and COVID-19: Initial Results From SECURE-CELIAC.

Clin Gastroenterol Hepatol. 2021-11

[6]
Gastrointestinal Manifestations of Pediatric Coronavirus Disease and Their Relationship with a Severe Clinical Course: A Systematic Review and Meta-analysis.

J Trop Pediatr. 2021-5-17

[7]
Prevalence and Persistent Shedding of Fecal SARS-CoV-2 RNA in Patients With COVID-19 Infection: A Systematic Review and Meta-analysis.

Clin Transl Gastroenterol. 2021-4-9

[8]
COVID-19 in Children With Liver Disease.

Front Pediatr. 2021-3-11

[9]
Digestive system symptoms and function in children with COVID-19: A meta-analysis.

Medicine (Baltimore). 2021-3-19

[10]
SARS-CoV-2 and the Gastrointestinal Tract in Children.

Front Pediatr. 2021-2-22

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