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一项关于跨性别男性尿道并发症和结局的系统回顾和荟萃分析。

A systematic review and meta-analysis of urethral complications and outcomes in transgender men.

机构信息

Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College and Chang Gung University, Taoyuan, Taiwan.

Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College and Chang Gung University, Taoyuan, Taiwan.

出版信息

J Plast Reconstr Aesthet Surg. 2022 Jan;75(1):10-24. doi: 10.1016/j.bjps.2021.08.006. Epub 2021 Sep 4.


DOI:10.1016/j.bjps.2021.08.006
PMID:34607781
Abstract

BACKGROUND: Urologic problems, such as urethral fistulas and strictures, are among the most frequent complications occurring after phalloplasty. Although many studies have reported successful phalloplasty and urethral reconstruction with reliable outcomes in transgender men, no method has become standardized so far. This study aimed to summarize the results of reports on urological complications and outcomes in transgender men with respect to various types of urethral reconstruction. METHODS: A comprehensive literature search of PubMed, Scopus, and Google Scholar databases was conducted for studies related to phalloplasty in transsexuals. Data on various phallic urethral techniques, urethral complications, and outcomes were collected and analyzed using the random-effects model. RESULTS: A total of 21 studies (1,566 patients) were included: eight studies (1,061 patients) on "tube-in-tube," nine studies (273 patients) on "prelaminated flap," and six studies (221 patients) on "second flap." Compared with the tube-in-tube technique, the prelaminated flap was associated with a significantly higher urethral stricture/stenosis rate; however, there was no difference between the prelaminated flap and the second flap techniques. For all phalloplasty patients, the pool rate of urethral fistula or stenosis is 48.9%, the rate of the ability to void while standing is 91.5%, occurrence rate of tactile or erogenous sensation is 88%, the prosthesis complication rate is 27.9%, and patient-reported satisfactory outcome rate is 90.5%. CONCLUSION: Urethral reconstruction with a prelaminated flap was associated with a significantly higher urethral stricture rate and increased need of revision surgery compared with that observed using a skin flap. Overall, most patients were able to void while standing and were satisfied with the outcomes.

摘要

背景:尿道瘘和狭窄等泌尿系统问题是男变女外生殖器成形术后最常见的并发症之一。尽管许多研究报道了男变女外生殖器成形术和尿道重建的成功案例,并且取得了可靠的结果,但目前还没有一种方法得到标准化。本研究旨在总结各种类型尿道重建术后男变女患者发生泌尿系统并发症和结果的报告。

方法:对 PubMed、Scopus 和 Google Scholar 数据库进行了全面的文献检索,检索与跨性别者行外生殖器成形术相关的研究。使用随机效应模型收集和分析各种阴茎尿道技术、尿道并发症和结果的数据。

结果:共纳入 21 项研究(1566 例患者):8 项研究(1061 例患者)采用“管中管”技术,9 项研究(273 例患者)采用“预制皮瓣”技术,6 项研究(221 例患者)采用“第二皮瓣”技术。与“管中管”技术相比,预制皮瓣技术与更高的尿道狭窄/梗阻发生率相关;然而,预制皮瓣和第二皮瓣技术之间没有差异。对于所有行外生殖器成形术的患者,尿道瘘或狭窄的总体发生率为 48.9%,能站立排尿的比例为 91.5%,触觉或性敏感发生率为 88%,假体并发症发生率为 27.9%,患者报告满意度为 90.5%。

结论:与使用皮瓣相比,预制皮瓣尿道重建与更高的尿道狭窄发生率和更高的修复手术需求相关。总体而言,大多数患者能够站立排尿,对结果感到满意。

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引用本文的文献

[1]
A core outcome set for research on masculinizing genital gender-affirming surgery: international consensus results from the GenderCOS project.

EClinicalMedicine. 2025-7-1

[2]
Comparison of the Results of Phalloplasty Using Radial Free Forearm Flap and Anterolateral Thigh in Iran from 2014 to 2019.

Indian J Plast Surg. 2024-5-24

[3]
Patient-reported outcomes after one-stage neourethral reconstruction in transmen with phalloplasty-associated strictures and fistulas.

World J Urol. 2024-9-30

[4]
Validation of Lower Urinary Tract Symptom Questionnaire in the Transmasculine Population.

Int Urogynecol J. 2024-9

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