Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Talatpaşa Bulvarı, 06100, Altındağ/Ankara, Turkey.
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Lokman Hekim University, Sogutozu, 06510, Çankaya/Ankara, Turkey.
Neurol Sci. 2022 Apr;43(4):2791-2801. doi: 10.1007/s10072-021-05643-y. Epub 2021 Oct 4.
The aims of this study were (a) to examine the surface electromyography (sEMG) amplitude values of the lower limb muscles during stair climbing both between different functional levels of Duchenne muscular dystrophy (DMD), in comparison with healthy children, and (b) to investigate the relationships between sEMG amplitudes and physical performance.
sEMG amplitudes of the lower limbs of twenty-one children with DMD between levels I and III according to the Brooke Lower Extremity Functional Classification Scale and eleven healthy peers were evaluated by using sEMG during stair climbing task. Physical performance was evaluated by 6-min walk test and ascending 4-step timed performance test.
The lower limb sEMG amplitude values of children with DMD were statistically higher than healthy children (p < 0.001). sEMG amplitudes of the right (p = 0.01) and left (p = 0.003) biceps femoris, the right (p < 0.001) and left (p = 0.001) gastrocnemius medialis, and the right vastus lateralis (p = 0.02) muscles were higher in children with levels 2-3 than those in level 1. Moderate-to-strong relations were found between the gastrocnemius medialis and biceps femoris sEMG amplitudes and physical performance assessments (p < 0.05).
Increased sEMG amplitude values in the lower limbs during stair climbing task are thought to be caused by the effort to compensate for progressive muscle weakness and are associated with lower physical performance in children with DMD. Further, sEMG amplitude values are determined to increase as the functional level deteriorates.
NCT04287582 ( https://clinicaltrials.gov/ct2/show/NCT04287582?term=merve+bora&draw=2&rank=1 ).
本研究的目的是（a）比较不同功能水平的杜氏肌营养不良症（DMD）患儿与健康儿童之间在爬楼梯时下肢肌肉的表面肌电图（sEMG）振幅值，（b）探讨 sEMG 振幅值与身体机能之间的关系。
使用 sEMG 在爬楼梯任务期间评估 21 名根据 Brooke 下肢功能分类量表处于 1 级至 3 级的 DMD 患儿和 11 名健康同龄人下肢的 sEMG 振幅值。通过 6 分钟步行测试和上 4 步计时测试评估身体机能。
DMD 患儿的下肢 sEMG 振幅值明显高于健康儿童（p<0.001）。右侧（p=0.01）和左侧（p=0.003）股二头肌、右侧（p<0.001）和左侧（p=0.001）比目鱼肌和右侧股外侧肌（p=0.02）的 sEMG 振幅值在 2-3 级患儿中高于 1 级患儿。比目鱼肌和股二头肌的 sEMG 振幅值与身体机能评估之间存在中等到较强的关系（p<0.05）。
在爬楼梯任务中下肢 sEMG 振幅值的增加被认为是由于肌肉无力进行代偿，这与 DMD 患儿的身体机能下降有关。此外，sEMG 振幅值随着功能水平的恶化而增加。
NCT04287582（https://clinicaltrials.gov/ct2/show/NCT04287582？term=merve+bora&draw=2&rank=1）。
