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可调胃束带失败后行 150cm 胆胰支胃旁路术再次吻合:中期结果和单阶段与双阶段方法比较。

Revisional One Anastomosis Gastric Bypass with a 150-cm Biliopancreatic Limb After Failure of Adjustable Gastric Banding: Mid-Term Outcomes and Comparison Between One- and Two-Stage Approaches.

机构信息

Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, via di Grottarossa 1035-9, 00189, Rome, Italy.

Bariatric Surgery Unit, Clinique des Cedres, Ramsay Générale de Santé, Cornebarrieu, France.

出版信息

Obes Surg. 2021 Dec;31(12):5330-5341. doi: 10.1007/s11695-021-05728-9. Epub 2021 Oct 5.

Abstract

PURPOSE

Laparoscopic adjustable gastric banding (LAGB) was a common procedure worldwide but associated with a high rate of long-term failure. This study aims to evaluate the safety and effectiveness of conversion to one anastomosis gastric bypass (OAGB) after failed LAGB.

MATERIALS AND METHODS

We undertook a retrospective analysis of a prospectively maintained database in a tertiary referral center for bariatric surgery. All cases of revisional OAGB with a biliopancreatic limb (BPL) of 150 cm after failed LAGB performed between 2010 and 2016 were analyzed.

RESULTS

Overall, 215 patients underwent conversion from LAGB to OAGB. Indication for surgery was primary weight loss (WL) failure in 30.7% of cases and long-term complications in the remaining patients, with or without associated weight regain. At the time of OAGB, the mean age was 43.2 ± 10.5 years and the mean BMI was 42 ± 6.9. Overall postoperative morbidity was 13.5%. The postoperative abscess ± leak rate was 5.9% in the overall population. Two years after OAGB, 9.7% of patients were lost to follow-up, % excess weight loss (EWL) was 88.2 ± 23.9, and % total weight loss (TWL) was 38.7 ± 9.3. At 5 years, 16.6% of patients were lost to follow-up, %EWL was 82.4 ± 25, and %TWL was 36.1 ± 10. There was no statistical difference in complication rates or WL results between the one-stage and two-stage approaches.

CONCLUSION

OAGB with a 150-cm BPL represents a safe and effective option after failed LAGB. Both synchronous OAGB and two-step revisional OAGB guarantee satisfying results in terms of postoperative morbidity and WL outcomes.

摘要

目的

腹腔镜可调节胃束带术(LAGB)在全球范围内是一种常见的手术,但长期失败率较高。本研究旨在评估 LAGB 失败后转换为单吻合口胃旁路术(OAGB)的安全性和有效性。

材料和方法

我们对一家三级转诊中心的前瞻性维持的减肥手术数据库进行了回顾性分析。所有因 LAGB 失败后行 OAGB 并保留 150cm 胆胰支(BPL)的患者均纳入本研究。

结果

共有 215 例患者接受了从 LAGB 到 OAGB 的转换。手术指征为原发性减重(WL)失败,占 30.7%,其余患者因长期并发症而行手术,无论是否伴有体重反弹。行 OAGB 时,患者平均年龄为 43.2±10.5 岁,平均 BMI 为 42±6.9。总体术后并发症发生率为 13.5%。总体人群术后脓肿+漏的发生率为 5.9%。OAGB 术后 2 年,9.7%的患者失访,% excess weight loss (EWL) 为 88.2±23.9,% total weight loss (TWL) 为 38.7±9.3。术后 5 年,16.6%的患者失访,%EWL 为 82.4±25,%TWL 为 36.1±10。单阶段和双阶段手术在并发症发生率和 WL 结果方面无统计学差异。

结论

LAGB 失败后行 150cm BPL 的 OAGB 是一种安全有效的选择。同步 OAGB 和两步法修订 OAGB 均可保证术后并发症发生率和 WL 结果满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e7a/8595146/1803d84d6d87/11695_2021_5728_Fig1_HTML.jpg

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