Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of General Surgery, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran.
Obes Surg. 2023 Dec;33(12):4080-4102. doi: 10.1007/s11695-023-06866-y. Epub 2023 Oct 25.
This systematic review and meta-analysis aimed to investigate the incidence of new-onset gastroesophageal reflux, reflux change, esophagitis, Barrett's esophagus, and revision due to reflux, gastritis, and marginal ulcer after one-anastomosis gastric bypass (OAGB). We performed subgroup analyses based on primary and revisional OAGB and time of follow-up. Meta-analysis of 87 studies with 27,775 patients showed a 6% rate of new-onset reflux after OAGB. Preoperative reflux status did not change significantly after OAGB. The rate of esophagitis and Barrett's esophagus was 15% and 1%, respectively. The new-onset reflux rate after OAGB was significantly higher than gastric bypass but not different with sleeve gastrectomy. The current study showed a relatively low rate of reflux and its complications after OAGB, but it was significantly higher than Roux-en-Y gastric bypass.
本系统评价和荟萃分析旨在调查胃旁路术后（OAGB）新发胃食管反流、反流变化、食管炎、巴雷特食管以及因反流、胃炎和边缘性溃疡而进行的再次手术的发生率。我们根据初次和再次 OAGB 以及随访时间进行了亚组分析。对 87 项研究、27775 例患者进行的荟萃分析显示，OAGB 后新发反流的发生率为 6%。OAGB 后术前反流状态无明显变化。食管炎和巴雷特食管的发生率分别为 15%和 1%。OAGB 后新发反流的发生率明显高于胃旁路术，但与袖状胃切除术无差异。本研究显示 OAGB 后反流及其并发症的发生率相对较低，但明显高于 Roux-en-Y 胃旁路术。
