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复杂脑动脉瘤血管内治疗器械的最新进展综合述评。

Comprehensive review of the recent advances in devices for endovascular treatment of complex brain aneurysms.

机构信息

Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

Interventional Neuroradiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

出版信息

Br J Radiol. 2022 Jan 1;95(1129):20210538. doi: 10.1259/bjr.20210538. Epub 2021 Oct 5.

Abstract

The International Subarachnoid Aneurysm Trial (ISAT) showed superiority for endovascular treatment of ruptured aneurysms and technology has since moved on rapidly. Many approaches and technology now exist for the endovascular management of ruptured and unruptured intracranial aneurysms, which reflects their varied nature - there is no one-size-fits-all technique. We aim to provide an overview of the various classes of device and the major developments over the past decade. Coiling is the oldest of the technology and continues to demonstrate high levels of occlusion and acceptable risks, making it the default treatment choice, particularly in the acutely ruptured aneurysm setting. Advances on coiling include the use of adjuncts such as balloons, stents and fully retrievable temporary neck-bridging devices, which have facilitated the treatment of more complex aneurysms. Flow divertors have also revolutionised complex aneurysm treatment with small added risk in acute aneurysm treatment and seek to remodel the aneurysm-vessel interface without accessing the aneurysm sac. The latest development and most promising avenue appears to be intrasaccular flow disrupting devices like WEB, Contour and Neqstent that provide excellent opportunities to treat wide neck complex aneurysm with minimal mortality and morbidity and good occlusion rates and may in future replace a significant number of stent-assisted coiling too.

摘要

国际蛛网膜下腔出血试验(ISAT)表明血管内治疗破裂动脉瘤具有优势,此后技术迅速发展。目前有许多方法和技术可用于治疗破裂和未破裂的颅内动脉瘤,这反映了它们的多样性——没有一种技术适用于所有情况。我们旨在概述过去十年中各种类别的设备和主要进展。

线圈是最古老的技术,它继续显示出高闭塞率和可接受的风险,使其成为默认的治疗选择,特别是在急性破裂动脉瘤的情况下。线圈的改进包括使用辅助设备,如球囊、支架和完全可回收的临时颈部桥接装置,这些设备使更复杂的动脉瘤的治疗变得更加容易。

血流导向装置也彻底改变了复杂动脉瘤的治疗方法,在急性动脉瘤治疗中增加了微小的风险,试图在不进入动脉瘤囊的情况下重塑动脉瘤-血管界面。最新的发展和最有前途的途径似乎是瘤内血流阻断装置,如 WEB、Contour 和 Neqstent,它们为治疗宽颈复杂动脉瘤提供了极好的机会,死亡率和发病率低,闭塞率高,并且可能在未来取代大量的支架辅助线圈。

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