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从 Guy 结石评分系统角度比较大于 2cm 的肾结石经皮肾镜碎石取石术与逆行性肾内手术的疗效。

Comparison of percutaneous nephrolithotomy and retrograde intrarenal surgery outcomes for kidney stones larger than 2 cm from Guy's stone scoring system perspective.

机构信息

Department of Urology, Ankara City Hospital, Ankara, Turkey.

Department of Urology Affiliated with Ankara City Hospital, Faculty of Medicine, University of Health Sciences, Ankara, Turkey.

出版信息

Int J Clin Pract. 2021 Dec;75(12):e14956. doi: 10.1111/ijcp.14956. Epub 2021 Oct 11.

DOI:10.1111/ijcp.14956
PMID:34614286
Abstract

OBJECTIVE

To compare surgical outcomes of percutaneous nephrolithotomy (PNL) and retrograde intrarenal surgeries (RIRS) as a result of kidney stones larger than 2 cm, together with Guy's stone scores (GSS).

MATERIALS AND METHODS

The data of 811 patients with stone sizes 2-6 cm were operated using PNL (n = 361) and RIRS (n = 450) reviewed retrospectively. GSS were graded 1, 2, 3 or 4 according to the computed tomography findings. Stone-free rate (SFR), operation times, length of hospital stay (LOHS) and Clavien complications (CC) were recorded.

RESULTS

Although mean operative times were significantly longer in the RIRS group than the PNL group in GSS grades 1, 2 and 3 (P < .001), it was similar between the two groups in GSS grade 4 (P = .186). SFRs in the PNL and RIRS group were 90.3% and 58.4% on post-operative 10th day (P < .001), and it raised up to 95.3% and 81.6% after secondary interventions (P < .001). Significantly higher SFRs observed in the PNL group in GSS grades 1, 2 and 3 categories. On postoperative 10th day, the SFRs were similar in both GSS grade 4 categories (P = .06). LOHS was longer in the PNL group (P < .001). Although LOHS was significantly longer only in GSS grade 3 (P = .043) and GSS grade 4 (P < .001) in the PNL group, it was similar in GSS grade 1 and 2 between groups. Clavien complications increased in line with GSS in the PNL group (P < .001), but the difference did not differ between GSS grade 3 and 4.

CONCLUSION

SF of PNL in a single session and short operation time seems to be significant especially in GSS grades 1, 2 and 3 category stones. Although the number of patients in the GSS 4 group is very small to claim this, RIRS might be considered as an alternative to PNL in a special group of patients such as GSS grade 4 because of its lower complication rates and shorter LOHS.

摘要

目的

比较经皮肾镜取石术(PNL)和逆行性肾内手术(RIRS)治疗>2cm 肾结石的手术效果,同时评估 Guy 结石评分(GSS)。

材料与方法

回顾性分析 811 例 2-6cm 肾结石患者的资料,其中 361 例行 PNL 治疗,450 例行 RIRS 治疗。根据 CT 结果,GSS 分级为 1、2、3 或 4 级。记录无结石率(SFR)、手术时间、住院时间(LOHS)和 Clavien 并发症(CC)。

结果

在 GSS 1、2 和 3 级时,RIRS 组的平均手术时间明显长于 PNL 组(P<.001),但在 GSS 4 级时两组相似(P=.186)。PNL 组和 RIRS 组术后第 10 天的 SFR 分别为 90.3%和 58.4%(P<.001),二次干预后分别提高至 95.3%和 81.6%(P<.001)。在 GSS 1、2 和 3 级中,PNL 组的 SFR 明显更高。术后第 10 天,两组 GSS 4 级的 SFR 相似(P=.06)。PNL 组的 LOHS 较长(P<.001)。虽然在 PNL 组中,GSS 3 级(P=.043)和 GSS 4 级(P<.001)的 LOHS 显著更长,但两组 GSS 1 级和 2 级的 LOHS 相似。PNL 组的 Clavien 并发症与 GSS 呈正相关(P<.001),但 3 级和 4 级之间的差异无统计学意义。

结论

单次 PNL 的结石清除率和短手术时间似乎具有重要意义,特别是在 GSS 1、2 和 3 级结石中。虽然 GSS 4 级的患者数量很少,但由于其并发症发生率较低和 LOHS 较短,RIRS 可能成为该类患者的一种替代治疗方法。

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