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以消化道出血为表现的转移性肾细胞癌

Metastatic Renal Cell Carcinoma Presenting as Gastrointestinal Bleeding.

作者信息

Hakim Christopher, Mendelson Avery, Patel Jalpa, Greer Julia, Sorser Serge

机构信息

Department of Internal Medicine, Ascension Providence Hospital - Michigan State University College of Human Medicine, Southfield, Michigan, USA.

Department of Gastroenterology, Ascension Providence Hospital - Michigan State University College of Human Medicine, Southfield, Michigan, USA.

出版信息

Case Rep Gastroenterol. 2021 Jun 2;15(2):478-481. doi: 10.1159/000514376. eCollection 2021 May-Aug.

Abstract

Approximately 85% of kidney tumors are renal cell carcinoma (RCC). RCC commonly metastasizes to the lung, bone, and lymph nodes; however, gastric metastasis is exceedingly rare. We present an 86-year-old woman with left-sided RCC with known metastatic disease to the lungs, lymph nodes, and bone, who presented with acute blood loss anemia. After hemodynamic stabilization, esophagogastroduodenoscopy revealed a large infiltrative, polypoid, and ulcerated polyp in the gastric body. After complete polypectomy, histological examination demonstrated gastric mucosa ulcerated by clear-cell carcinoma, compatible with metastatic RCC. Our patient was successfully treated with palliative radiation to the gastric body.

摘要

大约85%的肾肿瘤是肾细胞癌(RCC)。肾细胞癌通常会转移至肺、骨和淋巴结;然而,胃转移极为罕见。我们报告一名86岁女性,患有左侧肾细胞癌,已知已转移至肺、淋巴结和骨,她因急性失血性贫血就诊。在血流动力学稳定后,食管胃十二指肠镜检查发现胃体有一个大的浸润性、息肉样且溃疡的息肉。完整切除息肉后,组织学检查显示胃黏膜被透明细胞癌溃疡,符合转移性肾细胞癌。我们的患者接受了胃体姑息性放疗,治疗成功。

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