Al Juboori Alhareth, Kaur Satinder, Reddy Atigadda
University of Missouri School of Medicine, Columbia, MO, USA.
Veterans Affairs Medical Center, University of Nevada School of Medicine, Reno, NV, USA.
Case Rep Gastrointest Med. 2017;2017:2509294. doi: 10.1155/2017/2509294. Epub 2017 Jun 21.
Renal cell carcinoma (RCC) accounts for approximately 3% of all adult malignancies. True gastrointestinal metastases, specifically to gastric wall, have been rarely observed. Herein we describe a case of delayed metastasis to gastric wall occurring more than a decade after previously curative nephrectomy for RCC. A 67-year-old male with history of right radical nephrectomy in 2001 for RCC was found to have an asymptomatic right lower lobe solitary lung mass upon routine follow-up in 2011, with final biopsy results showing metastatic RCC for which he was treated accordingly. In 2014, patient was evaluated for dyspepsia with microcytic anemia and underwent an esophagogastroduodenoscopy and colonoscopy. EGD revealed a solitary one-centimeter atypical ulcer in the posterior mid gastric body with biopsy results being consistent with metastatic RCC. Our literature review has yielded thirty-six reported cases of RCC in association with gastric wall metastases.
肾细胞癌(RCC)约占所有成人恶性肿瘤的3%。真正的胃肠道转移,特别是转移至胃壁的情况,很少被观察到。在此,我们描述一例在先前因RCC行根治性肾切除术后十多年出现的胃壁延迟转移病例。一名67岁男性,2001年因RCC行右肾根治性切除术,2011年常规随访时发现右肺下叶有一个无症状的孤立性肺肿块,最终活检结果显示为转移性RCC并据此进行了治疗。2014年,该患者因消化不良伴小细胞性贫血接受评估,并接受了食管胃十二指肠镜检查和结肠镜检查。食管胃十二指肠镜检查发现胃体后壁有一个1厘米的孤立性非典型溃疡,活检结果与转移性RCC一致。我们的文献综述共发现36例报告的RCC合并胃壁转移病例。