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溶解性寄生:一例骨破坏型包虫病

Lytic parasitic: a case of bone destructing echinococcosis.

作者信息

Govindasamy Avaan, Bhattarai Pushpa Raj, John Jeff

机构信息

Division of General Surgery, Department of Surgery, Frere Hospital and Walter Sisulu University, East London 5200, South Africa.

Division of General Surgery, Department of Surgery, Frere Hospital and Walter Sisulu University, East London, South Africa.

出版信息

Ther Adv Infect Dis. 2021 Sep 29;8:20499361211047664. doi: 10.1177/20499361211047664. eCollection 2021 Jan-Dec.

Abstract

Pelvic hydatid bone disease is a rare and debilitating condition. Patients often present with symptoms and signs when the disease process is advanced and curative resection is not possible. We present a case of destructive bone hydatid disease affecting the left iliac bone. A 45-year-old woman presented initially 5 years ago with a left pelvic mass to the gynaecology department. Computed tomography (CT) scan done at that time showed a large pelvic, left iliac fossa cystic mass with the destruction of the left iliac bone. Extension of the cystic mass transversed the iliac bone into the posterior soft tissue. Percutaneous biopsy taken showed hydatid cystic disease. The patient was planned for surgery and, however, was lost to follow-up. Four years later, she presented with a history of worsening left pelvic pain with an enlarging, left pelvic mass, and another mass in the posterior gluteal area. In addition, CT imaging showed extensive left iliac bone destruction with posterior soft tissue extension to the gluteus muscle. A multidisciplinary team concluded that complete excision would not result in cure. Thus, complete iliac wing bone reconstruction was not an option in this patient. Instead, palliative measures were deemed in the patient's best interest to control disease progression and relieve painful pressure-related symptoms from the hydatid cystic mass. The patient received preoperative albendazole and underwent an extraperitoneal debulking of the soft tissue hydatid infiltration and debridement of bony fragments from left iliac bone destruction. Postoperatively, the patient did well, and her main complaint of pain related to the cystic mass pressure had improved significantly.

摘要

盆腔包虫骨病是一种罕见且使人衰弱的疾病。当疾病进展到晚期且无法进行根治性切除时,患者常出现症状和体征。我们报告一例累及左髂骨的破坏性骨包虫病病例。一名45岁女性5年前最初因左盆腔肿物就诊于妇科。当时的计算机断层扫描(CT)显示左髂窝有一个大的盆腔囊性肿物,伴有左髂骨破坏。囊性肿物延伸穿过髂骨进入后软组织。经皮活检显示为包虫囊肿病。该患者计划接受手术,但失访。四年后,她因左盆腔疼痛加重、左盆腔肿物增大以及臀后区出现另一个肿物前来就诊。此外,CT成像显示左髂骨广泛破坏,后软组织延伸至臀肌。一个多学科团队得出结论,完全切除无法治愈。因此,对该患者来说,完全重建髂骨翼不是一个选择。相反,为了控制疾病进展并缓解包虫囊肿肿物引起的与压力相关的疼痛症状,认为采取姑息措施符合患者的最大利益。患者术前接受了阿苯达唑治疗,并接受了腹膜外减瘤手术,切除软组织包虫浸润灶并清除左髂骨破坏处的骨碎片。术后,患者情况良好,她主要的与囊肿肿物压力相关的疼痛主诉明显改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e4c/8488500/691cb32892f8/10.1177_20499361211047664-fig1.jpg

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