Björlin G, Ljungnér H, Astedt B
Acta Odontol Scand. 1986 Jun;44(3):173-5. doi: 10.3109/00016358609026570.
Plasminogen activators in alveolar bone in man was studied in quenching experiments by a fibrin slide technique with addition of monospecific antibodies against tissue plasminogen activators (t-PA) and urokinase (u-PA). The plasminogen activator activity was quenched in the slides with anti-t-PA. No quenching was observed in the slides with anti-u-PA. This does not exclude the possibility that enzymatically inactive pre-urokinase is present.
通过纤维蛋白玻片技术并添加针对组织纤溶酶原激活物(t-PA)和尿激酶(u-PA)的单特异性抗体,在淬灭实验中研究了人牙槽骨中的纤溶酶原激活物。在添加抗t-PA的玻片中,纤溶酶原激活物活性被淬灭。在添加抗u-PA的玻片中未观察到淬灭现象。这并不排除存在无酶活性的前尿激酶的可能性。