National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After V.I.Kulakov, of the Ministry of Healthcare of Russian Federation, Moscow, Russia.
National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After V.I.Kulakov, of the Ministry of Healthcare of Russian Federation, Moscow, Russia.
Biosystems. 2021 Dec;210:104558. doi: 10.1016/j.biosystems.2021.104558. Epub 2021 Oct 5.
Antral follicle growth and recruitment are the basis of female reproduction. Follicular wave theory explains the recruitment, growth, and selection of antral follicles. This article is devoted to the follicular wave pattern in female reproduction throughout life. We highlight progress in understanding the rhythmic follicle changes based on clinical studies and studies on animal models. We review the follicular wave pattern before puberty, during pregnancy, and in perimenopause. Several mathematical models are known which quite accurately describe follicular wave dynamics. The follicular waves theory allows the implementation of the new approaches to ovarian stimulation. Stimulation in the luteal phase and double stimulation are used more widely nowadays for fertility preservation in cancer patients and for increasing the chances of IVF programs success in poor responder patients.
窦卵泡生长和募集是女性生殖的基础。卵泡波理论解释了窦卵泡的募集、生长和选择。本文致力于阐述女性一生中生殖的卵泡波模式。我们根据临床研究和动物模型研究，强调了对周期性卵泡变化的理解进展。我们回顾了青春期前、怀孕期间和围绝经期的卵泡波模式。目前已经有几种数学模型可以相当准确地描述卵泡波动力学。卵泡波理论允许实施新的卵巢刺激方法。黄体期刺激和双刺激现在更广泛地用于癌症患者的生育力保存和增加 IVF 方案在低反应患者中成功的机会。
