Scott Terence P, Sharma Sanjib K, Wallace Ryan M, Nel Louis H, Adhikari Samir K, Abela-Ridder Bernadette, Thumbi S M
Global Alliance for Rabies Control, Manhattan, KS, 66502, USA.
Department of Internal Medicine, B P Koirala Institute of Health Sciences, Dharan, Nepal.
Toxicon X. 2021 Sep 25;12:100084. doi: 10.1016/j.toxcx.2021.100084. eCollection 2021 Nov.
Both rabies and snakebite primarily affect underserved and impoverished communities globally, with an estimated 200,000 people dying from these diseases annually, and the greatest burden being in Africa and Asia. Both diseases have been neglected and have thus been denied appropriate prioritization, support, and interventions, and face many of the challenges common to all neglected tropical diseases (NTDs). In line with the call for integrated approaches between NTDs in the recent NTD Roadmap, we sought to build upon previous conceptualizations for an integrated approach by identifying the commonalities between snakebite and rabies to explore the feasibility of an integrated approach. While multiple areas for potential integration are identified, we highlight the potential pitfalls to integrating rabies and snakebite programs, considering the nuances that make each disease and its intervention program unique. We conclude that health system strengthening, and capacity building should be the focus of any integrated approach among NTDs, and that by strengthening overall health systems, both rabies and snakebite can advocate for further support from governments and stakeholders.
狂犬病和蛇咬伤主要影响全球服务不足和贫困的社区,估计每年有20万人死于这些疾病,其中非洲和亚洲负担最重。这两种疾病都被忽视了,因此没有得到适当的优先重视、支持和干预,并且面临着所有被忽视热带病(NTDs)共有的许多挑战。根据最近的NTD路线图中对NTDs综合方法的呼吁,我们试图通过确定蛇咬伤和狂犬病之间的共性,在以往综合方法概念的基础上,探索综合方法的可行性。虽然确定了多个潜在的整合领域,但考虑到使每种疾病及其干预计划独特的细微差别,我们强调了整合狂犬病和蛇咬伤计划的潜在陷阱。我们得出结论,加强卫生系统和能力建设应成为NTDs任何综合方法的重点,并且通过加强整体卫生系统,狂犬病和蛇咬伤都可以争取政府和利益相关者的进一步支持。