Lantheaume Sophie, Fernandez Lydia, Lantheaume Stéphane, Moták Ladislav, Conceição Stéphanie Blois-Da
Hôpital Privé Drôme Ardèche, 07 500, Guilherand-Granges, France.
Laboratoire Inter-universitaire de Psychologie : Personnalité, Cognition et Changement Social (LIP PC2S), Université Grenoble Alpes, 38 400, Saint-Martin-d'Hères, France.
Support Care Cancer. 2022 Mar;30(3):1935-1943. doi: 10.1007/s00520-021-06203-y. Epub 2021 Oct 8.
In women with breast cancer, many disease-related psychosocial factors directly affect quality of life (QoL) during and after treatment. The aims of this prospective study were to evaluate the psychosocial factors affecting QoL and its dimensions, to study their evolution over time, and to determine the factors associated with this evolution.
Thirty women with non-metastatic breast cancer were asked to complete a number of questionnaires evaluating QoL and its dimensions, symptoms of anxiety and depression, body image, social support, and coping strategies immediately after their diagnosis of breast cancer (T1), at the end of treatment (T2), and 6 months after the end of treatment (T3).
Level of education, mastectomy, and hormonotherapy all had an impact on QoL. QoL and its dimensions changed over time. Coping strategies, social support, body image, and symptoms of anxiety and depression were predictive factors for QoL.
The identification of these predictive factors should help medical teams to identify the patients who are most vulnerable and susceptible to poor QoL. In women with breast cancer, it is essential to identify and treat any changes in patients' need for support in an appropriate manner, both during the course of therapy and particularly during remission.
在乳腺癌女性患者中，许多与疾病相关的社会心理因素直接影响治疗期间及治疗后的生活质量（QoL）。这项前瞻性研究的目的是评估影响生活质量及其维度的社会心理因素，研究它们随时间的变化，并确定与这种变化相关的因素。
30名非转移性乳腺癌女性患者在确诊乳腺癌后即刻（T1）、治疗结束时（T2）以及治疗结束6个月后（T3），被要求完成多项评估生活质量及其维度、焦虑和抑郁症状、身体意象、社会支持和应对策略的问卷。
教育水平、乳房切除术和激素治疗均对生活质量有影响。生活质量及其维度随时间变化。应对策略、社会支持、身体意象以及焦虑和抑郁症状是生活质量的预测因素。
识别这些预测因素应有助于医疗团队识别出生活质量最易受影响且最可能较差的患者。对于乳腺癌女性患者，在治疗过程中，尤其是在缓解期，以适当方式识别并处理患者支持需求的任何变化至关重要。
