State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China (J.Z., X.H., Z.L., H.L., X.Q., M.Z., X.R., X.C., G.J., X.G., X.T., L.L. Y.L.); Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China (J.Z., X.H., Z.L., H.L., X.Q., M.Z., X.R., X.C., G.J., X.G., X.T., L.L. Y.L.).
Department of Ophthalmology, the Sixth Affiliated Hospital of Sun Yat-sen University (Z.X.), Guangzhou, Guangdong, China.
Am J Ophthalmol. 2022 Feb;234:241-249. doi: 10.1016/j.ajo.2021.09.035. Epub 2021 Oct 6.
To investigate the prediction accuracy of intraocular lens (IOL) calculation formulas, and the impact of anterior chamber depth (ACD) and lens thickness (LT) measurement errors on IOL power calculation in patients undergoing combined phakic IOL (PIOL) removal and cataract surgery.
Retrospective, consecutive case series study.
Thirty-six PIOL implanted eyes (12 anterior chamber PIOLs and 24 posterior chamber PIOLs [PC-PIOL]) undergoing cataract surgery were included. The prediction accuracy of new formulas (Barrett universal II, Emmetropia verifying optical, Kane, and Ladas super formula) and traditional formulas (Haigis, Hoffer Q, Holladay 1 and SRK/T) with or without Wang-Koch (WK) axial length (AL) adjustment was evaluated. The influence of ACD and LT measurement errors of IOLMaster 700 on refractive outcomes was also investigated.
The Kane and traditional formulas with WK AL adjustment had no significant systematic prediction error and displayed a smaller median absolute error, whereas the other formulas showed significant hyperopia shift (P < .05) and relatively lower prediction accuracy. The accuracy rate of IOLMaster 700 in measuring the ACD and LT was 100% in eyes with anterior chamber PIOL implantation, and 37.50% in the PC-PIOL subgroup. No significant difference was observed in refractive outcomes of formulas using correct and wrong parameters in the PC-PIOL subgroup (P > .05).
The Kane and traditional formulas with WK AL adjustment exhibited relatively higher prediction accuracy in patients who underwent combined PIOL removal and cataract surgery. The IOLMaster 700 displayed low accuracy in ACD and LT measurements for PC-PIOL implanted eyes, but showed negligible impact on IOL prediction accuracy.
研究人工晶状体（IOL）计算公式的预测准确性，以及前房深度（ACD）和晶状体厚度（LT）测量误差对行有晶状体眼人工晶状体（PIOL）取出联合白内障手术患者的 IOL 屈光力计算的影响。
回顾性、连续病例系列研究。
纳入 36 只植入 PIOL 的眼（12 只前房 PIOL 和 24 只后房 PIOL[PC-PIOL]）行白内障手术。评估新公式（Barrett 通用 II 型、正视验证光学、Kane 和 Ladas 超公式）和传统公式（Haigis、Hoffer Q、Holladay 1 和 SRK/T）以及有无 Wang-Koch（WK）眼轴（AL）校正的预测准确性。还研究了 IOLMaster 700 测量 ACD 和 LT 误差对屈光结果的影响。
Kane 公式和传统公式联合 WK AL 校正无显著系统预测误差，中位绝对误差较小，而其他公式显示明显远视漂移（P<.05）和相对较低的预测准确性。IOLMaster 700 在测量前房 PIOL 植入眼的 ACD 和 LT 时的准确率为 100%，而在 PC-PIOL 亚组中为 37.50%。在 PC-PIOL 亚组中，使用正确和错误参数的公式的屈光结果无显著差异（P>.05）。
在联合行 PIOL 取出和白内障手术的患者中，Kane 公式和传统公式联合 WK AL 校正显示出相对较高的预测准确性。IOLMaster 700 在测量 PC-PIOL 植入眼的 ACD 和 LT 时准确性较低，但对 IOL 预测准确性影响可忽略不计。
