State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China.
Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Transl Vis Sci Technol. 2023 Sep 1;12(9):16. doi: 10.1167/tvst.12.9.16.
To identify risk factors of ocular anterior segment measurement error by the IOLMaster 700 in eyes implanted with an implantable Collamer lens (ICL).
In total, 152 patients with clear lens (152 eyes, group 1) and another 32 cataract patients (57 eyes, group 2) who underwent ICL implantation were included, and the presence of measurement error by the IOLMaster 700 was determined based on B-scan images. The risk factors for measurement error were evaluated by logistic regression, and the optimal threshold was determined using receiver operating characteristic analysis.
The ICL was misidentified as the anterior surface of the crystalline lens in 51.97% of eyes (79/152) in group 1 and 80.70% of eyes (46/57) in group 2. For every 100-µm decrease in the vault height, a 3.57- and 5.78-fold increase in the risk of measurement error was observed in group 1 and group 2, respectively. We identified an optimal threshold of the vault height at 389.47 µm for predicting biometric measurement error in eyes implanted with ICL, which showed an area under the curve of 0.93 (95% confidence interval, 0.90-0.97), a sensitivity of 0.87, and a specificity of 0.86.
Patients with ICL implantation, particularly those with a vault height less than 389.47 µm, are at a greater risk of anterior segment biometric measurement error by the IOLMaster 700.
The threshold of vault height can help to identify high-risk patients and further optimize biometric measurement.
通过 IOLMaster 700 识别植入可植入 Collamer 透镜（ICL）后眼前节测量误差的危险因素。
共纳入 152 例透明晶状体（152 眼，第 1 组）和 32 例白内障患者（57 眼，第 2 组），根据 B 型扫描图像确定 IOLMaster 700 的测量误差是否存在。采用逻辑回归评估测量误差的危险因素，并通过受试者工作特征分析确定最佳阈值。
第 1 组中 51.97%（79/152）的眼和第 2 组中 80.70%（46/57）的眼将 ICL 错误识别为晶状体前表面。每减少 100 µm 的拱高，第 1 组和第 2 组的测量误差风险分别增加 3.57 倍和 5.78 倍。我们确定了一个预测 ICL 植入眼生物测量误差的最佳拱高阈值为 389.47 µm，曲线下面积为 0.93（95%置信区间，0.90-0.97），敏感度为 0.87，特异度为 0.86。
植入 ICL 的患者，尤其是拱高小于 389.47 µm 的患者，更容易发生 IOLMaster 700 眼前节生物测量误差。
“group 1”和“group 2”都是原文中出现的英文缩写，为了方便中国读者理解，我将其翻译成了中文。
“biometric measurement error”在原文中的意思是“生物测量误差”，是指在进行生物测量时，由于各种因素的影响，导致测量结果与实际值之间存在差异。
原文中出现了一些医学术语，如“anterior segment”（眼前节）、“ICL”（可植入 Collamer 透镜）、“vault height”（拱高）等，我在翻译时保留了这些术语，以便读者更好地理解文章内容。
