Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, 270 Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China.
Graefes Arch Clin Exp Ophthalmol. 2022 Apr;260(4):1345-1352. doi: 10.1007/s00417-021-05423-6. Epub 2021 Oct 9.
To investigate the impact of single-vision spectacle use on myopia progression in children with low myopia.
MYOSOTIS is a prospective myopia screening survey including all 46 primary and junior high schools in two districts of Hangzhou, China. After 1-to-1 propensity score matching (PSM), 1,685 pairs of students with low myopia were included. Group 1 was composed of 1,685 non-spectacle users at baseline, and group 2 consisted of 1,685 spectacle wearers at both survey rounds. Refraction was examined by noncycloplegic autorefraction and mean spherical equivalent refraction (SER) of both eyes was analyzed. Myopia progression was measured by average rate of change in SER (r∆SER) between two survey rounds and compared between the two groups.
After PSM, no significant difference in age, sex ratio, SER, and uncorrected visual acuity (VA) between the two groups was found at baseline. For myopic progression, r∆SER showed no significant difference between the two groups (- 0.67 ± 0.97 versus - 0.69 ± 0.81 diopter/year, P = 0.448). After adjusting for age, sex, SER, and VA, the difference in r∆SER between the two groups was not significant (- 0.031, 95% CI - 0.089 ~ 0.028 diopter/year, P = 0.302). In the subgroup analyses stratified by age and SER, and in the sensitivity analyses by eye side, there was still no significant difference in myopia progression between the two groups.
Our study indicates that single-vision spectacle use has no impact on myopia progression in children with low myopia. Spectacles are recommended in children with low myopia if their visual acuity has interfered with the daily life.
研究单焦镜对低度近视儿童近视进展的影响。
MYOSOTIS 是一项在中国杭州市两个区的所有 46 所小学和初中进行的前瞻性近视筛查调查。经过 1:1 倾向评分匹配（PSM）后，共纳入 1685 对低度近视的学生。第 1 组由基线时的 1685 名非眼镜使用者组成，第 2 组由两轮调查中均戴眼镜的 1685 名眼镜使用者组成。通过非睫状肌自动验光检查屈光度，分析双眼的平均球镜等效屈光度（SER）。通过两次调查之间 SER 的平均变化率（r∆SER）来衡量近视进展，并比较两组之间的差异。
PSM 后，两组在基线时的年龄、性别比、SER 和未矫正视力（VA）无显著差异。在近视进展方面，两组之间的 r∆SER 无显著差异（-0.67±0.97 与-0.69±0.81 屈光度/年，P=0.448）。在校正年龄、性别、SER 和 VA 后，两组之间 r∆SER 的差异不显著（-0.031，95%CI-0.089~0.028 屈光度/年，P=0.302）。在按年龄和 SER 分层的亚组分析以及按眼别进行的敏感性分析中，两组之间的近视进展仍无显著差异。
本研究表明，单焦镜对低度近视儿童的近视进展无影响。如果低度数近视儿童的视力影响日常生活，建议佩戴眼镜。
