COVID-19 幸存者伴环孢素治疗的类风湿关节炎。

COVID-19 survivors with calcineurin-inhibitors-treated rheumatoid arthritis.

机构信息

Department of Rheumatology, Tokyo Medical University Hachioji Medical Center, Hachioji, Tokyo, Japan.

Department of Infectious Diseases, Tokyo Medical University, Hachioji Medical Center, Hachioji, Tokyo, Japan.

出版信息

Mod Rheumatol Case Rep. 2022 Jan 7;6(1):10-13. doi: 10.1093/mrcr/rxab023.

DOI:10.1093/mrcr/rxab023

PMID:34626196

Abstract

We report two cases recovered from coronavirus disease 2019 with rheumatoid arthritis which had been in remission or low disease activity by taking calcineurin inhibitor (CNI). Both cases had moderate to severe pneumonia treated with intravenous dexamethasone or in the severe case remdesivir in addition to it. These cases suggest that the use of CNI may have affected the improvement of severe pneumonia.

摘要

我们报告了两例由冠状病毒病 2019 引起的病例，这两例患者患有类风湿关节炎，在服用钙调磷酸酶抑制剂（CNI）后处于缓解或低疾病活动状态。这两例患者均患有中重度肺炎，除静脉注射地塞米松外，重症患者还使用了瑞德西韦。这些病例表明，CNI 的使用可能影响了重症肺炎的改善。