[Correlation and difference analysis in parameters between video head impulse test and caloric test in vestibular disease].

To investigate interrelationships in parameters between caloric test and video head impulse test（vHIT） in the common peripheral vertigo diseases and healthy people, and to conduct correlation and difference analysis between the results in two tests, so as to evaluate the clinical diagnosis value of peripheral vertigo. The caloric test and vHIT were fulfilled in 68 patients with vertigo and 17 healthy volunteers. The diagnosis was done according to history inquiring, otology and audiology examination and vestibular tests. The vestibulo-ocular reflex（VOR） gain and gain asymmetry（GA） of a vHIT as well as unilateral weakness（UW） and the sum of the slow-phase velocities（SPVs） of warm and cold irrigation of the same side were compared. A cutoff value of VOR gain of a vHIT was also calculated using a receiver-operating characteristic curve. In all ears（=170）, there was significant correlation in ipsilateral SPVs and VOR gain（=0.568, <0.0001）; In all ears（=34） of 17 healthy volunteers, there was no correlation in ipsilateral SPVs and VOR gain（=-0.05, =0.778）; In all affected ears（=76）, there was statistically positive correlation in ipsilateral SPVs and VOR gain（=0.571, <0.0001）; In all the unaffected ears（=94）, there was positive correlation in ipsilateral SPVs and VOR gain（=0.286, =0.005）. In 60 patients with unilateral vestibular disease（=60）, there was statistically significant negative correlation between the VOR gain of affected ears and UW（=-0.513, <0.0001）; there was statistically significant positive correlation between GA of a vHIT and UW（=0.713, <0.0001）. There was a statistically significant negative correlation between the VOR gain of affected ears and UW in the fluctuating vertigo group（=-0.516, =0.002） as well as a positive correlation between GA and UW（=0.529, =0.001）; In the non-fluctuating vertigo group, there was a statistically significant negative correlation between the VOR gain of affected ears and UW（=-0.428, =0.029）; there was a positive correlation between GA of a vHIT and UW（=0.743, <0.0001）. In the vestibular neuropathy group, there was a negative correlation between the VOR gain of affected ears and UW（=-0.462, =0.030）; there was a statistically significant positive correlation between GA of a vHIT and UW（=0.757, <0.0001）. There was a negative correlation between the VOR gain of affected ears and UW in the vestibular peripheral disease group（=-0.516, =0.002） as well as a statistically significant positive correlation between GA and UW（=0.529, =0.001）. The mean value of UW（65.5%） was higher in the overt saccade group than that in the normal VOR group, there was statistically significant difference（=0.006）. According to the UW damage degree grading, there was statistically significant difference in abnormal educe rates（χ²=17.76, <0.05）. Based on the gold standard of caloric response, a cutoff value of 0.865 was determined; the parameters of the two tests were dissociated in 28.3%. There was a statistically significant correlation in parameters between vHIT and caloric test. The patients of overt saccade always accompany with the high UW, which could indicate that the vestibular function severely damaged. vHIT and caloric test can be complementary tools for the comprehensive evaluation of patients' vestibule function, on account of dissociation between the results of vHIT and caloric test and general result of consistent check.