Li Jun, Zhang Yunmei, Shi Chen, Liao Shuchen, Chen Nan, Yu Yafeng
Department of Otolaryngology，the First Affiliated Hospital of Soochow University，Suzhou，215006，China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Nov;36(11):854-858. doi: 10.13201/j.issn.2096-7993.2022.11.009.
To explore the correlation between the parameters of video head impulse test （vHIT）and dizziness handicap inventory （DHI） score in patients with vestibular neuritis. Clinical data of 46 patients with vestibular neuritis were retrospectively analyzed. All the patients underwent DHI evaluation and vHIT examination. They were divided into mild handicap group, moderate handicap group and severe handicap group according to DHI score. The correlations between the parameters of vHIT and DHI score were compared among the three groups. The important parameters of vHIT were compared including vestibulo-ocular reflex （VOR） gain, gain asymmetry ratio （GA）, abnormal saccade dispersion （PR%）. Of the 46 patients, 10 were in the mild handicap group, 21 in the moderate handicap group, and 15 in the severe handicap group. ①In the comparison of the mean value of lateral semicircular canal VOR gain, the vHIT gain of patients with mild, moderate and severe handicap were 0.64±0.06, 0.53±0.11 and 0.37±0.10, respectively, the mean value of VOR gain was negatively correlated with DHI score among the three groups（=-0.545, <0.001）, and the pairwise comparisons among the three groups was statistically significant（<0.05）. In comparison of the mean values of lateral semicircular canal GA, the GA values of mild, moderate and severe handicap groups were 46.40±21.81, 47.59±15.17 and 56.57±17.39, respectively, there was no significant linear correlation between GA values and DHI scores among the three groups（=0.246, >0.05）, there was no significant difference between the three groups（>0.05）. In comparison of the mean PR% of the lateral semicircular canal, the mean PR% of patients with mild, moderate and severe handicap group were 32.00±10.62, 53.82±17.09 and 76.00±10.01, respectively, PR% was positively correlated with DHI score（=0.726, <0.001）, and the comparison among the three groups was statistically significant（<0.05）. ②The vertical semicircular canal vHIT gain of patients with mild, moderate and severe handicap was 0.63±0.06, 0.52±0.15 and 0.38±0.16, respectively, the mean of VOR gain was negatively correlated with DHI score among the three groups（=-0.487, <0.01）, the comparison of mild-severe and moderate-severe group was statistically significant（<0.05）, while there was no significant difference between the mild and moderate group（>0.05）. In the comparison of the mean values of vertical semicircular canal GA, the GA values of mild, moderate and severe handicap groups were 40.40±15.31, 46.10±19.59 and 47.87±18.05, respectively, there was no significant linear correlation between GA values and DHI scores among the three groups（=0.047, >0.05）, there was no significant difference in GA among the three groups（>0.05）. The PR% of patients with mild, moderate and severe handicap were 42.40±15.39, 54.14±17.60 and 64.93±10.95, respectively, there was a positive significant correlation between PR% and DHI score（=0.454, <0.05）, there was statistically significant in the comparison of mild-severe group（<0.05）, while there was no statistical significance between the other groups（>0.05）. The VOR gain and PR% value of vHIT in patients with vestibular neuritis are closely related to the DHI score, which can evaluate the vestibular function and the degree of vertigo.
探讨前庭神经炎患者视频头脉冲试验（vHIT）参数与头晕残障量表（DHI）评分之间的相关性。回顾性分析46例前庭神经炎患者的临床资料。所有患者均接受DHI评估和vHIT检查。根据DHI评分将其分为轻度残障组、中度残障组和重度残障组。比较三组vHIT参数与DHI评分之间的相关性。比较vHIT的重要参数，包括前庭眼反射（VOR）增益、增益不对称率（GA）、异常扫视离散度（PR%）。46例患者中，轻度残障组10例，中度残障组21例，重度残障组15例。①在水平半规管VOR增益均值比较中，轻度、中度和重度残障患者的vHIT增益分别为0.64±0.06、0.53±0.11和0.37±0.10，三组中VOR增益均值与DHI评分呈负相关（=-0.545，<0.001），三组间两两比较差异有统计学意义（<0.05）。在水平半规管GA均值比较中，轻度、中度和重度残障组的GA值分别为46.40±21.81、47.59±15.17和56.57±17.39，三组中GA值与DHI评分之间无显著线性相关性（=0.246，>0.05），三组间差异无统计学意义（>0.05）。在水平半规管平均PR%比较中，轻度、中度和重度残障组患者的平均PR%分别为32.00±10.62、53.82±17.09和76.00±10.01，PR%与DHI评分呈正相关（=0.726，<0.001），三组间比较差异有统计学意义（<0.05）。②轻度、中度和重度残障患者的垂直半规管vHIT增益分别为0.63±0.06、0.52±0.15和0.38±0.16，三组中VOR增益均值与DHI评分呈负相关（=-0.487，<0.01），轻度-重度组和中度-重度组比较差异有统计学意义（<0.05），而轻度和中度组间差异无统计学意义（>0.05）。在垂直半规管GA均值比较中，轻度、中度和重度残障组的GA值分别为40.40±15.31、46.10±19.59和47.87±18.05，三组中GA值与DHI评分之间无显著线性相关性（=0.047，>0.05），三组间GA差异无统计学意义（>0.05）。轻度、中度和重度残障患者的PR%分别为42.40±15.39、54.14±17.60和64.93±10.95，PR%与DHI评分呈显著正相关（=0.454，<0.05），轻度-重度组比较差异有统计学意义（<0.05），而其他组间无统计学意义（>0.05）。前庭神经炎患者vHIT的VOR增益和PR%值与DHI评分密切相关，可用于评估前庭功能和眩晕程度。
