人类自噬测量：转化的一个被低估的障碍。
Human autophagy measurement: an underappreciated barrier to translation.
机构信息
Lysosomal Health in Ageing, Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.
Lysosomal Health in Ageing, Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.
出版信息
Trends Mol Med. 2021 Dec;27(12):1091-1094. doi: 10.1016/j.molmed.2021.09.003. Epub 2021 Oct 7.
Preclinical research shows that autophagy is a modifiable process that holds promise for preventing human age-related disease. However, this knowledge has not been clinically translated. Here, we discuss recent developments in the ability to measure human autophagy, and why it is a critical step for translation.
临床前研究表明，自噬是一种可调节的过程，有望预防人类与年龄相关的疾病。然而，这方面的知识尚未在临床上得到转化。在这里，我们讨论了目前在测量人类自噬能力方面的最新进展，以及为什么这是转化的关键步骤。
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