Prachanronarong Kristina, Kim Edward
Department of Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York, New York.
Semin Intervent Radiol. 2021 Oct;38(4):425-431. doi: 10.1055/s-0041-1735529. Epub 2021 Oct 7.
Radiation segmentectomy is an yttrium-90 transarterial radioembolization treatment where a high radiation dose is administered to a small volume of liver to achieve a high tumoricidal dose to a target with anatomic surgical precision while sparing surrounding parenchyma. This therapeutic modality is often used to treat hepatocellular carcinoma, and recent studies have demonstrated that radiation segmentectomy is an effective treatment as a neoadjuvant to transplant, resection, or as a standalone treatment. This article provides a review of radiation segmentectomy, indications for treatment, recent outcome data, and guidelines for postprocedural management.
放射性节段切除术是一种钇-90经动脉放射性栓塞治疗,将高辐射剂量施用于小体积肝脏,以在保留周围实质的同时,以解剖学手术精度对靶标实现高杀瘤剂量。这种治疗方式常用于治疗肝细胞癌,最近的研究表明,放射性节段切除术作为移植、切除的新辅助治疗或作为独立治疗是一种有效的治疗方法。本文综述了放射性节段切除术、治疗适应证、近期疗效数据以及术后管理指南。