Oliveira Marcelo Parente, Mello Roberto José Vieira DE, Montenegro Luciano Tavares, Paz Silvania Tavares, Lima Diego Ariel DE, Leite José Alberto Dias
Federal University of Cariri, Faculty of Medicine, Barbalha, CE, Brazil.
Federal University of Pernambuco, Department of Pathology, Recife, PE, Brazil.
Acta Ortop Bras. 2021 Sep-Oct;29(5):253-257. doi: 10.1590/1413-785220212905240286.
To quantify the neural elements in the posterior cruciate ligament (PCL) in healthy knees and with primary osteoarthrosis (OA).
In two groups with OA, one of cadavers and another of individuals, the area of neural elements identified in histological sections of PCL with anti-S100 immunohistochemistry was quantified.
The overall mean area of the neural elements was 0.96% ± 0.67%, with the value in the cadaver group of 1.02% ± 0.67% and in the OA group of 0.80% ± 0.64%, with a significant statistically difference (p = 0.001). No correlation was observed between neural element quantification and the age of the individuals (p > 0.05). There was no difference in the quantification of neural elements between the sexes in the cadaver group (p = 0.766), but in the OA group there was a statistically significant reduction in males (p = 0.003). Also, in the osteoarthrosis group there was no difference in the quantification of neural elements in the knees with varus or valgus alignment (p = 0.847).
There was a decrease in neural element quantification in PCL of individuals affected by OA in relation to non-arthritic individuals, with this quantification not related to age or with the axis of the lower limb. However, this quantification is not related to age or the axis of the lower limb.
量化健康膝关节以及原发性骨关节炎（OA）膝关节后交叉韧带（PCL）中的神经成分。
在两组OA患者中，一组为尸体组，另一组为个体组，通过抗S100免疫组织化学方法对PCL组织学切片中识别出的神经成分面积进行量化。
神经成分的总体平均面积为0.96%±0.67%，尸体组为1.02%±0.67%，OA组为0.80%±0.64%，差异具有统计学意义（p = 0.001）。未观察到神经成分量化与个体年龄之间存在相关性（p > 0.05）。尸体组中神经成分量化在性别之间无差异（p = 0.766），但在OA组中男性神经成分量化有统计学显著降低（p = 0.003）。此外，在骨关节炎组中，内翻或外翻膝关节的神经成分量化无差异（p = 0.847）。
与非关节炎个体相比，OA患者PCL中的神经成分量化减少，且这种量化与年龄或下肢轴线无关。然而，这种量化与年龄或下肢轴线无关。
