Ostojic Ana, Mrzljak Anna, Mikulic Danko
Department of Gastroenterology and Hepatology, University Hospital Center Zagreb, Zagreb 10000, Croatia.
Department of Surgery, University Hospital Merkur, Zagreb 10000, Croatia.
World J Hepatol. 2021 Sep 27;13(9):1098-1106. doi: 10.4254/wjh.v13.i9.1098.
Benign liver tumors are common lesions that are usually asymptomatic and are often found incidentally due to recent advances in imaging techniques and their widespread use. Although most of these tumors can be managed conservatively or treated by surgical resection, liver transplantation (LT) is the only treatment option in selected patients. LT is usually indicated in patients that present with life-threatening complications, when the lesions are diffuse in the hepatic parenchyma or when malignant transformation cannot be ruled out. However, due to the significant postoperative morbidity of the procedure, scarcity of available donor liver grafts, and the benign course of the disease, the indications for LT are still not standardized. Hepatic adenoma and adenomatosis, hepatic hemangioma, and hepatic epithelioid hemangioendothelioma are among the most common benign liver tumors treated by LT. This article reviews the role of LT in patients with benign liver tumors. The indications for LT and long-term outcomes of LT are presented.
良性肝肿瘤是常见病变,通常无症状,由于成像技术的最新进展及其广泛应用,常偶然发现。虽然这些肿瘤大多数可以保守处理或通过手术切除治疗,但肝移植(LT)是部分患者的唯一治疗选择。当患者出现危及生命的并发症、病变弥漫于肝实质或无法排除恶性转化时,通常会考虑肝移植。然而,由于该手术术后发病率高、可用供肝稀缺以及疾病的良性病程,肝移植的适应证仍未标准化。肝腺瘤和腺瘤病、肝血管瘤以及肝上皮样血管内皮瘤是接受肝移植治疗的最常见良性肝肿瘤。本文综述了肝移植在良性肝肿瘤患者中的作用。介绍了肝移植的适应证和长期疗效。