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应对卵巢癌肝转移:治疗方案的最新进展及多学科方法的必要性

Addressing hepatic metastases in ovarian cancer: Recent advances in treatment algorithms and the need for a multidisciplinary approach.

作者信息

Adamopoulou Konstantina, Gkamprana Athanasia M, Patsouras Konstantinos, Halkia Evgenia

机构信息

Department of Obstetrics and Gynecology, Tzaneio General Hospital, Pireaus 18536, Greece.

出版信息

World J Hepatol. 2021 Sep 27;13(9):1122-1131. doi: 10.4254/wjh.v13.i9.1122.

Abstract

The lifetime risk for ovarian cancer incidence is 1.39% and the lifetime risk of death is 1.04%. Most ovarian cancer patients are diagnosed at advanced stages (III, IV) because there were no specific symptoms or existing screening tests. Liver metastases have been found in up to 50% of patients dying of advanced ovarian cancer. Recent studies indicate the need for a multidisciplinary approach from initial diagnosis to oncologic surgery and chemotherapy treatment, mandating the involvement of gynecologic oncologists, surgical oncologist, medical oncologists, hepatobiliary surgeons, and interventional radiologists.

摘要

卵巢癌的终生发病风险为1.39%,终生死亡风险为1.04%。大多数卵巢癌患者在晚期(III期、IV期)被诊断出来,因为没有特定症状或现有的筛查测试。在死于晚期卵巢癌的患者中,高达50%发现有肝转移。最近的研究表明,从初始诊断到肿瘤手术和化疗治疗需要多学科方法,这就要求妇科肿瘤学家、外科肿瘤学家、医学肿瘤学家、肝胆外科医生和介入放射科医生参与其中。

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NCCN Guidelines Insights: Ovarian Cancer, Version 1.2019.NCCN 指南解读:卵巢癌,第 1.2019 版。
J Natl Compr Canc Netw. 2019 Aug 1;17(8):896-909. doi: 10.6004/jnccn.2019.0039.
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Surgical treatment of ovarian cancer liver metastasis.卵巢癌肝转移的外科治疗
Hepatobiliary Surg Nutr. 2019 Apr;8(2):129-137. doi: 10.21037/hbsn.2018.12.06.

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