氯美噻唑在健康青年和老年志愿者中的生物利用度及药效学：初步研究结果。

The bioavailability and pharmacodynamics of chlormethiazole in healthy young and elderly volunteers: preliminary findings.

作者信息

Jostell K G, Fagan D, Björk M, Broberg F, Mitchell R M, Scott D B, Ulff B

出版信息

Acta Psychiatr Scand Suppl. 1986;329:32-3. doi: 10.1111/j.1600-0447.1986.tb10532.x.

DOI:10.1111/j.1600-0447.1986.tb10532.x

Abstract

A preliminary analysis of a study of the bioavailability and pharmacodynamics of chlormethiazole in healthy young and elderly volunteers has been performed. The bioavailability assessed by a stable isotope method and the pharmacodynamic effects assessed by psychometric tests were found not to differ between the two age groups.

摘要

已对健康青年和老年志愿者进行了一项关于氯美噻唑生物利用度和药效学的研究的初步分析。通过稳定同位素法评估的生物利用度以及通过心理测量测试评估的药效学效应在两个年龄组之间未发现差异。