安乃近对人体前列腺素合成的影响。
The effects of metamizol on prostaglandin synthesis in man.
作者信息
Frölich J C, Rupp W A, Zapf R M, Badian M J
出版信息
Agents Actions Suppl. 1986;19:155-66.
PMID:3463174
Abstract
Clinical pharmacological investigations on the inhibition of prostaglandin synthesis are presented, comparing metamizol and indomethacin with respect to platelet aggregation, platelet thromboxane synthesis, total body PGE2-synthesis and side effects. Prostaglandin synthesis is clearly and persistently inhibited by metamizol in man.
摘要
本文介绍了关于抑制前列腺素合成的临床药理学研究，比较了安乃近和吲哚美辛对血小板聚集、血小板血栓素合成、全身PGE2合成及副作用的影响。安乃近在人体内能明显且持续地抑制前列腺素合成。
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