Katz A J, Rosen F S
Ciba Found Symp. 1977(46):243-61. doi: 10.1002/9780470720288.ch12.
Patients with B cell deficiency have a high incidence of prolonged Giardia lamblia infection of the gastrointestinal tract that causes symptoms of malabsorption with villus flattening. The changes are reversible with therapy directed against Giardia. There is a high incidence of pernicious anaemia in patients with agammaglobulinaemia. Those with abnormal B lymphocytes tend to develop lymphoid nodular hyperplasia. Gastrointestinal disease is rare in boys with X-linked agammaglobulinaemia when compared with adults with the 'acquired' or common variable form of the disease. T cell deficiency results in intractable diarrhoea and monilial infection of the gastrointestinal tract.
B细胞缺陷患者胃肠道贾第虫感染持续时间延长的发生率很高，这种感染会导致吸收不良症状并伴有绒毛变平。针对贾第虫的治疗可使这些改变逆转。无丙种球蛋白血症患者患恶性贫血的发生率很高。B淋巴细胞异常的患者往往会出现淋巴样结节增生。与患有“获得性”或常见可变型疾病的成人相比，患有X连锁无丙种球蛋白血症的男孩胃肠道疾病很少见。T细胞缺陷会导致顽固性腹泻和胃肠道念珠菌感染。
