Conroy T, Gaucher P, Bigard M A, Brucker P, Champigneulle B, Boman F
Sem Hop. 1984 Mar 8;60(11):786-91.
The observation of a 21 year-old man with primary common variable hypogammaglobulinemia and total villous atrophy is reported. Gluten withdrawal induced considerable improvement in malabsorption and mucosal damage. However, protein-losing enteropathy, nodular lymphoid hyperplasia and immunoglobulin deficiency were persistent. To our knowledge, improvement on gluten-free diet has been reported until now in 18 previous cases. This report illustrates the links between immunodeficiency and malabsorption, which are discussed.
报告了一名患有原发性常见可变型低丙种球蛋白血症和全绒毛萎缩的21岁男性的观察情况。停用麸质后,吸收不良和黏膜损伤有了显著改善。然而,蛋白丢失性肠病、结节性淋巴样增生和免疫球蛋白缺乏仍然存在。据我们所知,迄今为止,已有18例先前病例报告了无麸质饮食的改善情况。本报告阐述了免疫缺陷与吸收不良之间的联系,并对此进行了讨论。