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莪术:对其植物学、传统用途、植物化学、药理学和毒理学的综述。

Curcumae Radix: a review of its botany, traditional uses, phytochemistry, pharmacology and toxicology.

机构信息

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu, China.

出版信息

J Pharm Pharmacol. 2022 Jun 9;74(6):779-792. doi: 10.1093/jpp/rgab126.

DOI:10.1093/jpp/rgab126
PMID:34633034
Abstract

OBJECTIVES

Curcumae Radix, the medicinal part is radix, commonly called as Yujin (Chinese:), is a widely used traditional Chinese medicine for its high medicinal value and health benefits. Curcumae Radix has been used to treat conditions such as syndrome of heat disease and unconsciousness, epilepsy and internal stagnation of phlegm, qi stagnation and blood stasis, dysmenorrhoea, jaundice, cholelithiasis caused by dampness heat of liver and gallbladder. This review aims to summarize the botany, traditional usages, processing, phytochemistry, quality control, pharmacology and toxicology of Curcumae Radix to better understand its therapeutic potential.

KEY FINDINGS

So far, a variety of chemical constituents have been isolated and identified from Curcumae Radix, mainly including volatile oil and diphenylheptanes. Modern research shows that the extracts and compounds from Curcumae Radix possess wide-ranging pharmacological effects, including anti-tumour, hepatoprotective, anti-inflammatory and analgesic, anti-thrombosis, as well as effects on the nervous system and others.

SUMMARY

Curcumae Radix holds an important position in traditional system of medicine. It is cost-effective and an important plant with curative application in contemporary medicine. However, further in-depth studies are also needed to determine the medical uses of this plant and its chemical constituents, pharmacological activity, quality control and toxicology.

摘要

目的

姜黄,药用部位是根茎,通常称为郁金(中文:),因其药用价值高和保健功效而被广泛用作传统中药。姜黄已被用于治疗热病和昏迷、癫痫和痰气郁结、气滞血瘀、痛经、黄疸、肝胆湿热所致的胆结石等病症。本综述旨在总结姜黄的植物学、传统用途、炮制、植物化学、质量控制、药理学和毒理学,以更好地了解其治疗潜力。

主要发现

迄今为止,已从姜黄中分离鉴定出多种化学成分,主要包括挥发油和二苯庚烷。现代研究表明,姜黄的提取物和化合物具有广泛的药理作用,包括抗肿瘤、保肝、抗炎和镇痛、抗血栓形成以及对神经系统等的作用。

总结

姜黄在传统医学体系中占有重要地位。它是一种具有成本效益的重要植物,在当代医学中有治疗应用。然而,也需要进一步深入研究来确定这种植物及其化学成分、药理活性、质量控制和毒理学的药用用途。

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