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具有OKT 8表型的急性淋巴细胞白血病手镜细胞。

Acute lymphoblastic leukemia hand-mirror cells with OKT 8 phenotype.

作者信息

Liso V, Specchia G, Pavone V, Riezzo A, Santorsola D, De Tullio L, Magno M

出版信息

Blut. 1986 Oct;53(4):315-9. doi: 10.1007/BF00320891.

Abstract

Acute lymphoblastic leukemia with hand-mirror cells (ALL-HMC) was diagnosed in a 20-year old patient. Cytochemical investigations revealed a positive reaction for PAS and acid phosphatase. Lymphoid blast cells were studied with various monoclonal antibodies in order to determine their derivation and differentiation. The data obtained (positivity for Leu 9, OKT 11 and OKT 8) suggest that blast cells were of T lineage with OKT 8 phenotype. This report supports the phenotypic heterogeneity of ALL-HMC.

摘要

一名20岁患者被诊断为伴有手镜细胞的急性淋巴细胞白血病(ALL-HMC)。细胞化学检查显示糖原染色(PAS)和酸性磷酸酶呈阳性反应。为了确定其来源和分化,使用多种单克隆抗体对淋巴母细胞进行了研究。获得的数据(Leu 9、OKT 11和OKT 8呈阳性)表明母细胞为具有OKT 8表型的T细胞系。本报告支持ALL-HMC的表型异质性。

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