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具有OKT 8表型的急性淋巴细胞白血病手镜细胞。

Acute lymphoblastic leukemia hand-mirror cells with OKT 8 phenotype.

作者信息

Liso V, Specchia G, Pavone V, Riezzo A, Santorsola D, De Tullio L, Magno M

出版信息

Blut. 1986 Oct;53(4):315-9. doi: 10.1007/BF00320891.

DOI:10.1007/BF00320891
PMID:3463369
Abstract

Acute lymphoblastic leukemia with hand-mirror cells (ALL-HMC) was diagnosed in a 20-year old patient. Cytochemical investigations revealed a positive reaction for PAS and acid phosphatase. Lymphoid blast cells were studied with various monoclonal antibodies in order to determine their derivation and differentiation. The data obtained (positivity for Leu 9, OKT 11 and OKT 8) suggest that blast cells were of T lineage with OKT 8 phenotype. This report supports the phenotypic heterogeneity of ALL-HMC.

摘要

一名20岁患者被诊断为伴有手镜细胞的急性淋巴细胞白血病(ALL-HMC)。细胞化学检查显示糖原染色(PAS)和酸性磷酸酶呈阳性反应。为了确定其来源和分化,使用多种单克隆抗体对淋巴母细胞进行了研究。获得的数据(Leu 9、OKT 11和OKT 8呈阳性)表明母细胞为具有OKT 8表型的T细胞系。本报告支持ALL-HMC的表型异质性。

相似文献

1
Acute lymphoblastic leukemia hand-mirror cells with OKT 8 phenotype.具有OKT 8表型的急性淋巴细胞白血病手镜细胞。
Blut. 1986 Oct;53(4):315-9. doi: 10.1007/BF00320891.
2
Acute lymphoblastic leukemia hand-mirror cells. Study of nine cases.
Blut. 1983 Nov;47(5):297-306. doi: 10.1007/BF00319899.
3
[Immunologic cell markers in acute lymphoblastic leukemia in children].[儿童急性淋巴细胞白血病中的免疫细胞标志物]
Eksp Onkol. 1987;9(2):28-30.
4
Hand-mirror variant of acute lymphoblastic leukemia. Evidence for early T-cell lineage in two cases by evaluation with monoclonal antibodies.急性淋巴细胞白血病的手镜样变异型。两例经单克隆抗体评估显示早期T细胞系的证据。
Cancer. 1985 Jan 1;55(1):77-83. doi: 10.1002/1097-0142(19850101)55:1<77::aid-cncr2820550113>3.0.co;2-a.
5
Acute lymphoblastic leukemia--hand mirror variant. An analysis of a large group of patients.急性淋巴细胞白血病——手持镜变异型。一大组患者的分析。
Am J Hematol. 1979;7(1):11-7. doi: 10.1002/ajh.2830070103.
6
Acute lymphoblastic leukemia--hand mirror cell variant: a detailed cytological and ultrastructural study with an analysis of the immunologic surface markers.急性淋巴细胞白血病——手镜细胞变异型:一项详细的细胞学和超微结构研究,并对免疫表面标志物进行分析
Am J Hematol. 1978;4(1):67-77. doi: 10.1002/ajh.2830040109.
7
Immunopathology of non-Hodgkin lymphomas.非霍奇金淋巴瘤的免疫病理学
Klin Wochenschr. 1984 Nov 2;62(21):1001-10. doi: 10.1007/BF01711721.
8
[Cells of the "hand mirror" type in lymphoblastic leukemia in children].
Eksp Onkol. 1988;10(1):46-9.
9
Pre-T cell lineage of hand-mirror cells in acute lymphoblastic leukemia.急性淋巴细胞白血病中手镜细胞的前T细胞谱系
Thymus. 1981 Feb;2(4-5):281-6.
10
A case of hand mirror cell variant of acute lymphoblastic leukemia.一例急性淋巴细胞白血病手镜细胞变异型病例。
Acta Med Okayama. 1980 Sep;34(4):283-7. doi: 10.18926/AMO/30519.

本文引用的文献

1
Hand-mirror cells in acute lymphoblastic leukemia.急性淋巴细胞白血病中的手镜细胞。
Am J Clin Pathol. 1981 Aug;76(2):240-1. doi: 10.1093/ajcp/76.2.240a.
2
Acute lymphoblastic leukemia--hand mirror variant--viral immune interrelationship as demonstrated by ultrastructural studies.急性淋巴细胞白血病——手持镜变体——超微结构研究显示的病毒免疫相互关系
Am J Hematol. 1981 Jun;10(4):399-403. doi: 10.1002/ajh.2830100410.
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Antigen--antibody complexes related to the baboon endogenous virus in humans with acute lymphoblastic leukemia--hand mirror variant (ALL-HMC).
Blood. 1980 Oct;56(4):661-6.
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Acute lymphoblastic leukemia: hand mirror variant.
Arch Pathol Lab Med. 1980 Mar;104(3):134-6.
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A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor.一种似乎能识别人类T细胞生长因子受体的单克隆抗体;该受体的部分特性
Nature. 1982 Nov 18;300(5889):267-9. doi: 10.1038/300267a0.
6
Acute lymphoblastic leukemia hand-mirror cells. Study of nine cases.
Blut. 1983 Nov;47(5):297-306. doi: 10.1007/BF00319899.
7
A defect in the formation of uropod-bearing lymphocytes (hand-mirror cells) in patients with the Wiskott-Aldrich syndrome.患有威斯科特-奥尔德里奇综合征的患者中,含尾足淋巴细胞(手镜细胞)形成存在缺陷。
Am J Hematol. 1981;10(2):157-63. doi: 10.1002/ajh.2830100207.
8
Amoeboid movement configuration. A cell configuration observed in tumour cells from 3 cases of bone marrow neoplasia.
Scand J Haematol. 1974;13(4):294-304. doi: 10.1111/j.1600-0609.1974.tb00273.x.
9
Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.从人血中分离单核细胞和粒细胞。通过一次离心分离单核细胞,通过离心和1g沉降相结合的方法分离粒细胞。
Scand J Clin Lab Invest Suppl. 1968;97:77-89.
10
Hand-mirror variant of acute lymphoblastic leukemia. Evidence for early T-cell lineage in two cases by evaluation with monoclonal antibodies.急性淋巴细胞白血病的手镜样变异型。两例经单克隆抗体评估显示早期T细胞系的证据。
Cancer. 1985 Jan 1;55(1):77-83. doi: 10.1002/1097-0142(19850101)55:1<77::aid-cncr2820550113>3.0.co;2-a.