Aga Khan University Hospital, Karachi, Pakistan.
J Pak Med Assoc. 2021 Aug;71(Suppl 5)(8):S45-S50.
To evaluate the oncological and functional outcomes of bone tumour patients who underwent reconstruction with mega prosthesis.
A retrospective study was conducted in the department of Orthopaedics Aga Khan University Hospital, Karachi. All the paediatric and adult age group patients diagnosed with malignant, benign and metastatic bone tumours and meeting the inclusion criteria were selected and analysed. Retrospective data was collected from January 2008-January 2018.
Sixty-two patients, 30 (48.4%) females and 32 (51.6%) males. were included in the study. Of these 57 (92%) cases had involvement of the lower limb. The mean age was 36.95±19.1 years with a range of 9-81 years. The duration of patients follow up was from 1-124 months (mean 32.7±36.43 months). There were 29 (47%) malignant cases. The most commonly occurring tumour site was distal femur and proximal femur. There were 53 (85%) primary surgeries (first time conducted surgeries) while 9(15%) revision surgeries were done. Major complications were encountered in 19 (30.6%) patients and 13 (20.9%) had minor complications. Post-surgery local recurrence occurred in 2 (3.2%) patients while 7 (11.2%) had distant metastasis. In functional outcomes the mean MSTS score of our patients was 72.09±26.43. The survival rate was 69.8% with 45 patients recovered.
With a good patient selection, adherence to the principles of tumour surgery and an adequate applied knowledge of mega prosthesis insertion, a good functional outcome was achieved.
评估接受巨型假体重建的骨肿瘤患者的肿瘤学和功能结果。
这是一项在卡拉奇 Aga Khan 大学医院骨科系进行的回顾性研究。选择并分析了所有符合纳入标准的诊断为恶性、良性和转移性骨肿瘤的儿科和成年患者。回顾性数据收集自 2008 年 1 月至 2018 年 1 月。
共有 62 名患者（30 名女性，占 48.4%；32 名男性，占 51.6%）纳入研究。其中 57 例（92%）为下肢受累。平均年龄为 36.95±19.1 岁，范围为 9-81 岁。患者的随访时间为 1-124 个月（平均 32.7±36.43 个月）。有 29 例（47%）为恶性病例。最常见的肿瘤部位是股骨远端和股骨近端。53 例（85%）为原发性手术（首次手术），9 例（15%）为翻修手术。19 例（30.6%）患者发生重大并发症，13 例（20.9%）发生轻微并发症。术后局部复发 2 例（3.2%），远处转移 7 例（11.2%）。在功能结果方面，我们患者的平均 MSTS 评分为 72.09±26.43。存活率为 69.8%，45 例患者康复。
通过良好的患者选择、遵循肿瘤外科原则以及对巨型假体插入术的充分应用知识，可实现良好的功能结果。
