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肾移植术后腹壁并发症:临床综述。

Abdominal wall complications after kidney transplantation: A clinical review.

机构信息

General Surgery Unit, University Hospital of Catania, Catania, Italy.

Cardiology Unit, University Hospital of Catania, Catania, Italy.

出版信息

Clin Transplant. 2021 Dec;35(12):e14506. doi: 10.1111/ctr.14506. Epub 2021 Oct 28.

Abstract

INTRODUCTION

Abdominal wall complications are common after kidney transplantation, and although they have a minor impact on patient and graft survival, they increase the patient's morbidity and may have an impact on quality of life. Abdominal wall complications have an overall incidence of 7.7-21%.

METHODS

This review will explore the natural history of abdominal wall complications in the kidney transplant setting, with a special focus on wound dehiscence and incisional herni, with a particular emphasis on risk factors, clinical characteristics, and treatment.

RESULTS

Many patient-related risk factors have been suggested, including older age, obesity, and smoking, but kidney transplant recipients have an additional risk related to the use of immunosuppression. Wound dehiscence usually does not require surgical intervention. However, for deep dehiscence involving the fascial layer with concomitant infection, surgical treatment and/or negative pressure wound therapy may be required.

CONCLUSIONS

Incisional hernia (IH) may affect 1.1-18% of kidney transplant recipients. Most patients require surgical treatment, either open or laparoscopic. Mesh repair is considered the gold standard for the treatment of IH, since it is associated with a low rate of postoperative complications and an acceptable rate of recurrence. Biologic mesh could be an attractive alternative in patients with graft exposition or infection.

摘要

引言

腹部壁并发症在肾移植后很常见,尽管它们对患者和移植物的存活率影响较小,但会增加患者的发病率,并可能影响生活质量。腹部壁并发症的总体发生率为 7.7-21%。

方法

本综述将探讨肾移植背景下腹部壁并发症的自然史,特别关注切口裂开和切口疝,重点关注危险因素、临床特征和治疗。

结果

许多与患者相关的风险因素已被提出,包括年龄较大、肥胖和吸烟,但肾移植受者还有与免疫抑制使用相关的额外风险。切口裂开通常不需要手术干预。然而,对于涉及筋膜层且伴有感染的深部裂开,可能需要手术治疗和/或负压伤口治疗。

结论

切口疝(IH)可能影响 1.1-18%的肾移植受者。大多数患者需要手术治疗,无论是开放性还是腹腔镜性。网片修复被认为是 IH 治疗的金标准,因为它与术后并发症发生率低和可接受的复发率相关。对于有移植物暴露或感染的患者,生物网片可能是一种有吸引力的替代物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ae8/9285099/177ed7a79a99/CTR-35-0-g002.jpg

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