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脊柱手术后结局的种族差异:系统评价和荟萃分析。

Racial Disparities in Outcomes After Spine Surgery: A Systematic Review and Meta-Analysis.

机构信息

Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA; Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.

Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.

出版信息

World Neurosurg. 2022 Jan;157:e232-e244. doi: 10.1016/j.wneu.2021.09.140. Epub 2021 Oct 8.

Abstract

OBJECTIVE

Racial disparities are a major issue in health care but the overall extent of the issue in spinal surgery outcomes is unclear. We conducted a systematic review/meta-analysis of disparities in outcomes among patients belonging to different racial groups who had undergone surgery for degenerative spine disease.

METHODS

We searched Ovid MEDLINE, Scopus, Cochrane Review Database, and ClinicalTrials.gov from inception to January 20, 2021 for relevant articles assessing outcomes after spine surgery stratified by race. We included studies that compared outcomes after spine surgery for degenerative disease among different racial groups.

RESULTS

We found 30 studies that met our inclusion criteria (28 articles and 2 published abstracts). We included data from 20 cohort studies in our meta-analysis (3,501,830 patients), which were assessed to have a high risk of observation/selection bias. Black patients had a 55% higher risk of dying after spine surgery compared with white patients (relative risk [RR], 1.55, 95% confidence interval [CI], 1.28-1.87; I = 70%). Similarly, black patients had a longer length of stay (mean difference, 0.93 days; 95% CI, 0.75-1.10; I = 73%), and higher risk of nonhome discharge (RR, 1.63; 95% CI, 1.47-1.81; I = 89%), and 30-day readmission (RR, 1.45; 95% CI, 1.03-2.04; I = 96%). No significant difference was noted in the pooled analyses for complication or reoperation rates.

CONCLUSIONS

Black patients have a significantly higher risk of unfavorable outcomes after spine surgery compared with white patients. Further work in understanding the reasons for these disparities will help develop strategies to narrow the gap among the racial groups.

摘要

目的

种族差异是医疗保健中的一个主要问题,但在脊柱手术结果中,这一问题的总体程度尚不清楚。我们对不同种族患者接受退行性脊柱疾病手术的结果进行了系统评价/荟萃分析。

方法

我们从 Ovid MEDLINE、Scopus、Cochrane Review Database 和 ClinicalTrials.gov 中检索了从成立到 2021 年 1 月 20 日的相关文章,评估了按种族分层的脊柱手术后的结果。我们纳入了比较不同种族组退行性脊柱疾病手术后结果的研究。

结果

我们发现了 30 项符合纳入标准的研究(28 篇文章和 2 篇已发表的摘要)。我们的荟萃分析纳入了 20 项队列研究的数据(3501830 名患者),这些研究被评估为存在观察/选择偏倚的高风险。与白人患者相比,黑人患者脊柱手术后死亡的风险高 55%(相对风险 [RR],1.55;95%置信区间 [CI],1.28-1.87;I = 70%)。同样,黑人患者的住院时间更长(平均差异,0.93 天;95%CI,0.75-1.10;I = 73%),非家庭出院的风险更高(RR,1.63;95%CI,1.47-1.81;I = 89%),30 天再入院的风险更高(RR,1.45;95%CI,1.03-2.04;I = 96%)。在并发症或再次手术率的汇总分析中,没有发现显著差异。

结论

与白人患者相比,黑人患者脊柱手术后的不良结局风险显著更高。进一步研究这些差异的原因将有助于制定缩小不同种族群体之间差距的策略。

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