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CGM 衍生指标——血糖管理指标,在评估非白种糖尿病个体的血糖控制中的作用。

Usefulness of CGM-Derived Metric, the Glucose Management Indicator, to Assess Glycemic Control in Non-White Individuals With Diabetes.

机构信息

Joslin Diabetes Center, Boston, MA

Beth Israel Deaconess Medical Center, Boston, MA.

出版信息

Diabetes Care. 2021 Dec;44(12):2787-2789. doi: 10.2337/dc21-1373. Epub 2021 Oct 11.

Abstract

OBJECTIVE

To assess the relationship between the glucose management indicator (GMI) and HbA in non-White individuals with diabetes.

RESEARCH DESIGN AND METHODS

We performed a retrospective analysis of continuous glucose monitoring metrics in individuals with diabetes divided by race into non-White and White cohorts.

RESULTS

We evaluated 316 individuals (non-White = 68; White = 248). Although GMI was not different (7.6 vs. 7.7; = not significant) between the cohorts, HbA was higher in the non-White cohort (8.7% vs. 8.1%; = 0.004). HbA higher than GMI by ≥0.5% was more frequently observed in the non-White cohort (90% vs. 75%; = 0.02). In the non-White cohort only, duration of hypoglycemia was longer among those with HbA higher than GMI by ≥0.5% compared with those with HbA and GMI within 0.5%.

CONCLUSIONS

A differential relationship between HbA and GMI in non-White versus White individuals with diabetes was observed. In non-White individuals, a greater difference between HbA and GMI was associated with higher risk of hypoglycemia.

摘要

目的

评估血糖管理指标(GMI)与糖尿病非白种人群中 HbA 的关系。

研究设计和方法

我们对按种族分为非白种人和白种人队列的糖尿病患者的连续血糖监测指标进行了回顾性分析。

结果

我们评估了 316 名患者(非白种人=68 人;白种人=248 人)。尽管两个队列的 GMI 没有差异(7.6 与 7.7;=无统计学意义),但非白种人队列的 HbA 更高(8.7%与 8.1%;=0.004)。HbA 比 GMI 高≥0.5%的情况在非白种人队列中更为常见(90%与 75%;=0.02)。仅在非白种人队列中,HbA 比 GMI 高≥0.5%的患者的低血糖持续时间长于 HbA 和 GMI 均在 0.5%以内的患者。

结论

在患有糖尿病的非白种人和白种人个体中,HbA 和 GMI 之间存在差异关系。在非白种人个体中,HbA 和 GMI 之间的差异越大,低血糖的风险越高。

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