Faculty of Medicine, Department of Obstetrics and Gynecology, University of Debrecen, Debrecen, Hungary.
Obstetrics and Gynecology Unit, Department of General Surgery and Medical Surgical Specialties, University of Catania, Italy.
Minim Invasive Ther Allied Technol. 2022 Jun;31(5):797-802. doi: 10.1080/13645706.2021.1986845. Epub 2021 Oct 12.
To evaluate the diagnostic accuracy of a bygone method, hystero-salpingo-scintigraphy (HSSG), for tubal patency assessment of infertile women.
Prospective cohort study involving women in the infertility workup at the University of Debrecen, Hungary. Seventy infertile patients were scheduled to either basic dynamic HSSG, post-purge dynamic HSSG, or post-purge dynamic HSSG followed by SPECT/CT for reducing tracer contamination. The primary endpoint was the evaluation of the diagnostic accuracy of HSSG for the three methods.
During the basic dynamic group, the examination yielded a sensitivity of 87.5%, with a specificity of 71.7%, while positive and negative predictive values were 31.8%, and 97.4% respectively. Using post purge dynamic HSSG, it resulted in a sensitivity of 87.5%, a specificity of 88.7%, a positive predictive value of 53.8%, and a negative predictive value of 97.9%. Adding SPECT/CT to post-purge dynamic HSSG increased diagnostic accuracy with 100% sensitivity and 88.7% specificity, while positive and negative predictive values were 57.1% and 100%, respectively.
HSSG is a non-invasive and well-tolerated technique for tubal patency. It could be used initially to predict tubal patency in case of infertility. Its diagnostic accuracy is higher when it is carried out by adding SPECT/CT to the post-purge dynamic method.
评估一项已过时的方法——子宫输卵管闪烁造影术（Hystero-salpingo-scintigraphy，HSSG）用于评估不孕女性输卵管通畅性的诊断准确性。
这是一项在匈牙利德布勒森大学进行的不孕患者评估的前瞻性队列研究。70 名不孕患者被安排接受基础动态 HSSG、灌洗后动态 HSSG 或灌洗后动态 HSSG 加 SPECT/CT 检查以减少示踪剂污染。主要终点是评估 HSSG 在这三种方法中的诊断准确性。
在基础动态组中，该检查的敏感性为 87.5%，特异性为 71.7%，阳性和阴性预测值分别为 31.8%和 97.4%。使用灌洗后动态 HSSG，其敏感性为 87.5%，特异性为 88.7%，阳性预测值为 53.8%，阴性预测值为 97.9%。在灌洗后动态 HSSG 中加入 SPECT/CT 可提高诊断准确性，敏感性为 100%，特异性为 88.7%，阳性预测值为 57.1%，阴性预测值为 100%。
HSSG 是一种非侵入性且耐受性良好的输卵管通畅性评估技术。它可以在不孕症的初始阶段用于预测输卵管通畅性。当将 SPECT/CT 添加到灌洗后动态方法中时，其诊断准确性更高。
